| Protein: | wwp-1 |
| Organism: | Caenorhabditis elegans |
| Length: | 794 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for wwp-1.
| Description | E-value | Query Range |
Subject Range |
|
|
578.0 | [0..1] | [794..1] |
|
Region A: Residues: [1-218] |
1 11 21 31 41 51
| | | | | |
1 MARNEPSSQQ PSSSGSNGTP AQQNGSAKPS KVTVKVVNAS FTKAADCYVE ITSDTSSAAP 60
61 KKTTVKKKTM APEWNEHLNV HANESSTISF RLLQKAKLFD DTCLGMAKLK LSSLTRNENG 120
121 EFKNDINNIS LLAKDSSKIG TLNIIFSGYP ERKRRSAGVR AETAASASSE ASTSNGVATS 180
181 SSARRPATAK RDTLAAPTST AAAAAAATAG GTPAAGAE
|
| Detection Method: |  |
| Confidence: | 24.39794 |
| Match: | 1dqvA |
| Description: | Synaptogamin I |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [219-399] |
1 11 21 31 41 51
| | | | | |
1 EQLPDGWEMR FDQYGRKYYV DHTTKSTTWE RPSTQPLPQG WEMRRDPRGR VYYVDHNTRT 60
61 TTWQRPTADM LEAHEQWQSG RDQAMLQWEQ RFLLQQNNFS ADDPLGPLPE GWEKRQDPNT 120
121 SRMYFVNHVN RTTQWEDPRT QGFRGSDQPL PDGWEMRFTE QGVPFFIDHQ SKTTTYNDPR 180
181 T
|
| Detection Method: | |
| Confidence: | 3.32 |
| Match: | 1tk7A |
| Description: | NMR structure of WW domains (WW3-4) from Suppressor of Deltex |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 3.13196227814032 | bayes_pls_golite062009 |
| ubiquitin-protein ligase activity | 2.50663692075518 | bayes_pls_golite062009 |
| transcription regulator activity | 2.38996385458463 | bayes_pls_golite062009 |
| small conjugating protein ligase activity | 2.33627990300135 | bayes_pls_golite062009 |
| transcription activator activity | 1.7271283334564 | bayes_pls_golite062009 |
| transcription factor binding | 1.70374758907671 | bayes_pls_golite062009 |
| histone methyltransferase activity | 1.67021314973391 | bayes_pls_golite062009 |
| acid-amino acid ligase activity | 1.64250861692227 | bayes_pls_golite062009 |
| transcription cofactor activity | 1.5022756775252 | bayes_pls_golite062009 |
| transcription coactivator activity | 1.33590567799099 | bayes_pls_golite062009 |
| protein binding | 1.27041711914941 | bayes_pls_golite062009 |
| protein methyltransferase activity | 0.9455445085372 | bayes_pls_golite062009 |
| protein-lysine N-methyltransferase activity | 0.863094487787088 | bayes_pls_golite062009 |
| lysine N-methyltransferase activity | 0.863094487787088 | bayes_pls_golite062009 |
| histone-lysine N-methyltransferase activity | 0.863094487787088 | bayes_pls_golite062009 |
| ligase activity, forming carbon-nitrogen bonds | 0.539489048525578 | bayes_pls_golite062009 |
| catalytic activity | 0.231344568578849 | bayes_pls_golite062009 |
| transcription repressor activity | 0.179456065780754 | bayes_pls_golite062009 |
|
Region A: Residues: [400-794] |
1 11 21 31 41 51
| | | | | |
1 GKPVGPLGVV GVQMAMEKSF RWKIAQFRYL CLSNSVPNHV KITVSRNNVF EDSFQEIMRK 60
61 NAVDLRRRLY IQFRGEEGLD YGGVAREWFF LLSHEVLNPM YCLFMYAGNN NYSLQINPAS 120
121 FVNPDHLKYF EYIGRFIAMA LFHGKFIYSG FTMPFYKKML NKKIVLKDIE QVDSEIYNSL 180
181 MWIKDNNIDE CDMELYFVAD YELLGELKTY ELKEGGTEIA VTEENKLEYI ELLVEWRFNR 240
241 GVEQQTKAFF TGFNSVFPLE WMQYFDEREL ELLLCGMQDV DVDDWQRNTV YRHYAPQSKQ 300
301 VTWFWQWVRS LDQEKRARLL QFVTGTCRVP VGGFSELMGS TGPQLFCIER VGKENWLPRS 360
361 HTCFNRLDLP PYRSYDQLVE KLSMAIEMTE GFGNE
|
| Detection Method: | |
| Confidence: | 119.0 |
| Match: | 1nd7A |
| Description: | Conformational Flexibility Underlies Ubiquitin Ligation Mediated by the WWP1 HECT domain E3 Ligase |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| ubiquitin-protein ligase activity | 7.14616396317218 | bayes_pls_golite062009 |
| small conjugating protein ligase activity | 6.99796579811325 | bayes_pls_golite062009 |
| acid-amino acid ligase activity | 6.03005793772151 | bayes_pls_golite062009 |
| ligase activity, forming carbon-nitrogen bonds | 4.50502148129705 | bayes_pls_golite062009 |
| sodium channel inhibitor activity | 3.64966529121446 | bayes_pls_golite062009 |
| binding | 3.09019421479054 | bayes_pls_golite062009 |
| ion channel inhibitor activity | 2.14402963004533 | bayes_pls_golite062009 |
| channel inhibitor activity | 2.14402963004533 | bayes_pls_golite062009 |
| ligase activity | 1.85936914071714 | bayes_pls_golite062009 |
| transcription regulator activity | 1.53041428769512 | bayes_pls_golite062009 |
| nucleic acid binding | 1.45373137371678 | bayes_pls_golite062009 |
| DNA binding | 1.32990029553036 | bayes_pls_golite062009 |
| protein binding | 1.29390544644063 | bayes_pls_golite062009 |
| sodium channel regulator activity | 1.19047973745862 | bayes_pls_golite062009 |
| catalytic activity | 1.15152367676155 | bayes_pls_golite062009 |
| transcription factor binding | 0.558655949211634 | bayes_pls_golite062009 |
| ubiquitin-ubiquitin ligase activity | 0.373649200425601 | bayes_pls_golite062009 |
| channel regulator activity | 0.072778668515899 | bayes_pls_golite062009 |
| 0.051942165438844 | bayes_pls_golite062009 |
