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View Structure Prediction Details

Protein: cfi-1
Organism: Caenorhabditis elegans
Length: 467 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cfi-1.

Description E-value Query
Range
Subject
Range
gi|197101491 - gi|197101491|ref|NP_001125719.1| jumonji, AT rich interactive domain 1C [Pongo abelii]
gi|55728964 - gi|55728964|emb|CAH91220.1| hypothetical protein [Pongo abelii]
254.0 [0..115] [412..10]

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Predicted Domain #1
Region A:
Residues: [1-160]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVRIDEPQL FVSMSKEPTQ ETVNVGGHHD DSSSNCDERV DDQTEEQKSP PASPDLTANL  60
   61 NVFDLESRQK VVQRLLNSQL NLSNLRAPLN LPPIFQALQG PFSIQQQLLG LASGLTAISP 120
  121 GLDDYDEENT NQGEPEDLTL GGFRKETSVK SEEPSESGIN 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [161-290]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASGPAWSYEE QFKQLYELSD DVKRKEWLDD WLNFMHRIGK PVTRIPIMAK QVLDLYELYR  60
   61 LVVQHGGLVE IINKKLWREI TKGLNLPSSI TSAAFTLRTQ YQKYLYDYEC EKEKLSNQSD 120
  121 LQQAIDGNRR 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 36.09691
Match: 1c20A
Description: DNA-binding domain from the dead ringer protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.19578385565784 bayes_pls_golite062009
DNA binding 0.71807968216163 bayes_pls_golite062009
transcription regulator activity 0.57049928754391 bayes_pls_golite062009
nucleic acid binding 0.121561704601947 bayes_pls_golite062009
protein binding 0.0208719739174101 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [291-402]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EAPGRRTAPS FPLPFQLPHA ASAAATMLNN QLNGLGMRND LLDDENTLSL QASGLFGTSY  60
   61 GAEQMAILEA HQRNLERAQR AVQQQVARQS LGLTACSNGN GGNIHNSGRE ST

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.02
Match: 1s1i9
Description: Structure of the ribosomal 80S-eEF2-sordarin complex from yeast obtained by docking atomic models for RNA and protein components into a 11.7 A cryo-EM map. This file, 1S1I, Contains 60S subunit. The 40S Ribosomal Subunit Is In File 1S1H.
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [403-467]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSNDSDIPAK RPKLENDVKT NGASSMRIST KHSDNSKTSM SVSMEINGIT YQGVLFALDE  60
   61 TVSES

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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Created and Maintained by: Michael Riffle