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View Structure Prediction Details

Protein: cfi-1
Organism: Caenorhabditis elegans
Length: 467 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cfi-1.

Description E-value Query
Range
Subject
Range
gi|197101491 - gi|197101491|ref|NP_001125719.1| jumonji, AT rich interactive domain 1C [Pongo abelii]
gi|55728964 - gi|55728964|emb|CAH91220.1| hypothetical protein [Pongo abelii]
254.0 [0..115] [412..10]

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Predicted Domain #1
Region A:
Residues: [1-160]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVRIDEPQL FVSMSKEPTQ ETVNVGGHHD DSSSNCDERV DDQTEEQKSP PASPDLTANL  60
   61 NVFDLESRQK VVQRLLNSQL NLSNLRAPLN LPPIFQALQG PFSIQQQLLG LASGLTAISP 120
  121 GLDDYDEENT NQGEPEDLTL GGFRKETSVK SEEPSESGIN 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [161-290]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASGPAWSYEE QFKQLYELSD DVKRKEWLDD WLNFMHRIGK PVTRIPIMAK QVLDLYELYR  60
   61 LVVQHGGLVE IINKKLWREI TKGLNLPSSI TSAAFTLRTQ YQKYLYDYEC EKEKLSNQSD 120
  121 LQQAIDGNRR 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 36.09691
Match: 1c20A
Description: DNA-binding domain from the dead ringer protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.19578385565784 bayes_pls_golite062009
DNA binding 0.71807968216163 bayes_pls_golite062009
transcription regulator activity 0.57049928754391 bayes_pls_golite062009
nucleic acid binding 0.121561704601947 bayes_pls_golite062009
protein binding 0.0208719739174101 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [291-402]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EAPGRRTAPS FPLPFQLPHA ASAAATMLNN QLNGLGMRND LLDDENTLSL QASGLFGTSY  60
   61 GAEQMAILEA HQRNLERAQR AVQQQVARQS LGLTACSNGN GGNIHNSGRE ST

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.02
Match: 1s1i9
Description: Structure of the ribosomal 80S-eEF2-sordarin complex from yeast obtained by docking atomic models for RNA and protein components into a 11.7 A cryo-EM map. This file, 1S1I, Contains 60S subunit. The 40S Ribosomal Subunit Is In File 1S1H.
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [403-467]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSNDSDIPAK RPKLENDVKT NGASSMRIST KHSDNSKTSM SVSMEINGIT YQGVLFALDE  60
   61 TVSES

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle