| Protein: | nhr-104 |
| Organism: | Caenorhabditis elegans |
| Length: | 395 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nhr-104.
| Description | E-value | Query Range |
Subject Range |
|
|
279.0 | [0..4] | [394..454] |
|
Region A: Residues: [1-90] |
1 11 21 31 41 51
| | | | | |
1 MRFNPCDVCL SPGNGKHFGV DACRGCTAFF RRTIVNKRNY SCSEDDTCEI EKSEGLLCKK 60
61 CRFEKCLKVG MKKESIQKHR DIYGRRNPEN
|
| Detection Method: |  |
| Confidence: | 22.69897 |
| Match: | 1lo1A |
| Description: | Steroid hormone receptor Err2 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 4.00967542385368 | bayes_pls_golite062009 |
| DNA binding | 3.60745514727532 | bayes_pls_golite062009 |
| nucleic acid binding | 3.47256374293954 | bayes_pls_golite062009 |
| binding | 2.96409924710655 | bayes_pls_golite062009 |
| transcription activator activity | 2.9532663930699 | bayes_pls_golite062009 |
| transcription factor activity | 2.90769972671972 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 2.72967350701574 | bayes_pls_golite062009 |
| protein binding | 2.44501340584871 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.40923942043513 | bayes_pls_golite062009 |
| ligand-dependent nuclear receptor activity | 1.49515149729803 | bayes_pls_golite062009 |
| transcription factor binding | 1.38523780690867 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.26452462867497 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 0.68943696300126 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.58115018700114 | bayes_pls_golite062009 |
| transcription repressor activity | 0.256420113528322 | bayes_pls_golite062009 |
| catalytic activity | 0.101795606736461 | bayes_pls_golite062009 |
|
Region A: Residues: [91-395] |
1 11 21 31 41 51
| | | | | |
1 RALIISPSTS QLQVTIPITL LSSVKRNYAE LENVREIVHR MDGFSMFLKP APRGQTYKET 60
61 YRLLLREFYL VSDWVSNCFP LFKELPNSQK DILLRNFYLT FYNLEAGFFA CQHNKIDVWF 120
121 LPNGNFIDCQ NLEAFYYDPH NQQPMTSADA ARLFKGTCTE CKRNVLEPML RENVTQFEFL 180
181 ALAALLLFDT GLEDQSDDCM DLCRNVRTLI QREMIQYYSN KHLDEYPLRM ADVISLIPRV 240
241 QKAAQKMQSD MEIGHLFNTY AAEKSFFENC MGKETSNEHN PSPRGGKFEN EKENSVFLII 300
301 GTIIP
|
| Detection Method: | |
| Confidence: | 34.39794 |
| Match: | 1xdkB |
| Description: | Crystal Structure of the RARbeta/RXRalpha Ligand Binding Domain Heterodimer in Complex with 9-cis Retinoic Acid and a Fragment of the TRAP220 Coactivator |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 5.53061626347066 | bayes_pls_golite062009 |
| DNA binding | 4.92165988569962 | bayes_pls_golite062009 |
| nucleic acid binding | 4.78024150262074 | bayes_pls_golite062009 |
| transcription activator activity | 4.53302455129434 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 4.11614358606713 | bayes_pls_golite062009 |
| transcription factor activity | 4.0914094580319 | bayes_pls_golite062009 |
| ligand-dependent nuclear receptor activity | 3.89763470197726 | bayes_pls_golite062009 |
| binding | 3.85318710398432 | bayes_pls_golite062009 |
| protein binding | 3.21524787168952 | bayes_pls_golite062009 |
| transcription factor binding | 2.68044489404568 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.38308182853979 | bayes_pls_golite062009 |
| steroid hormone receptor activity | 2.30195937604451 | bayes_pls_golite062009 |
| transcription repressor activity | 2.20686235000733 | bayes_pls_golite062009 |
| receptor activity | 2.07573173722434 | bayes_pls_golite062009 |
| transcription cofactor activity | 1.73827483890179 | bayes_pls_golite062009 |
| nuclear hormone receptor binding | 1.60419100774741 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.34794228300778 | bayes_pls_golite062009 |
| retinoic acid receptor binding | 1.28118886948947 | bayes_pls_golite062009 |
| transcription coactivator activity | 1.23834725221597 | bayes_pls_golite062009 |
| molecular transducer activity | 1.19872119297817 | bayes_pls_golite062009 |
| signal transducer activity | 1.19872119297817 | bayes_pls_golite062009 |
| retinoid X receptor binding | 0.99801784942981 | bayes_pls_golite062009 |
| retinoic acid receptor activity | 0.853869057774515 | bayes_pls_golite062009 |
| protein dimerization activity | 0.797229273848179 | bayes_pls_golite062009 |
| hormone receptor binding | 0.74373733735458 | bayes_pls_golite062009 |
| promoter binding | 0.58091332905515 | bayes_pls_golite062009 |
| protein N-terminus binding | 0.57701453824007 | bayes_pls_golite062009 |
| thyroid hormone receptor activity | 0.49784404390361 | bayes_pls_golite062009 |
| protein heterodimerization activity | 0.45265806678057 | bayes_pls_golite062009 |
| receptor binding | 0.418843034756825 | bayes_pls_golite062009 |
| ligand-regulated transcription factor activity | 0.202197503742221 | bayes_pls_golite062009 |
| lipid binding | 0.164046651023989 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity, enhancer binding | 0.15737167800277 | bayes_pls_golite062009 |
| catalytic activity | 0.106902059021677 | bayes_pls_golite062009 |
