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View Structure Prediction Details

Protein: vha-11
Organism: Caenorhabditis elegans
Length: 384 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for vha-11.

Description E-value Query
Range		 Subject
Range
VATC1_XENTR - V-type proton ATPase subunit C 1 OS=Xenopus tropicalis GN=atp6v1c1 PE=2 SV=1
 581.0 [0..6] [383..1]

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Predicted Domain #1
Region A:
Residues: [1-384] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSATSGEYW LISVPGEKGA NDAWDKLNRS TGNTSTNSKY LIPDLKVGTL DQLVGLSDDL  60
   61 SKLDTSAEAV IRKLVQYFTE VLEEDKSKIA ENLVIGNKDM KTYVTKFQWE GAKYPLKQSL 120
  121 KVLSEIIGKQ ISQIDNDLKV KSLTYNNLKN ALASMDRKTV GSLLTKDLAD LVKADDFVLN 180
  181 SEYLQTVIVV VPKISVKEWE QKYATLSSMV VPGSSKLLTE EGEHALYTVT LFKKVIDEFK 240
  241 NTARENKFIV RDFVYDEETL KAGRTERDKL MAEKQRQYAP LIRWLKINFG EIFAAYIHIK 300
  301 ALRVFVESVL RYGLPVNFQA AVIEPAKGQQ KKLRQELHKL YIHLDGSAAG PIDTLEDSPA 360
  361 LMSLGVNEYY PYVFFKLNID FLNK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 124.0
Match: 1u7lA
Description: Crystal Structure of subunit C (vma5p) of the yeast V-ATPase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrogen ion transmembrane transporter activity 12.3352255617459 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 10.5863459521035 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 9.47957751673845 bayes_pls_golite062009
proton-transporting ATPase activity, rotational mechanism 8.04670314838796 bayes_pls_golite062009
hydrogen-exporting ATPase activity, phosphorylative mechanism 7.25165353297621 bayes_pls_golite062009
cation-transporting ATPase activity 5.95289483482599 bayes_pls_golite062009
cation transmembrane transporter activity 5.74889738890923 bayes_pls_golite062009
ion transmembrane transporter activity 5.64669396672268 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 5.22844923180027 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions 4.07961473146848 bayes_pls_golite062009
transporter activity 3.46526113720851 bayes_pls_golite062009
transmembrane transporter activity 3.37048202892137 bayes_pls_golite062009
substrate-specific transporter activity 3.36986693191031 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism 3.01531981010483 bayes_pls_golite062009
primary active transmembrane transporter activity 2.60440013485447 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 2.60069637398921 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 2.58215499145116 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 2.57906484106374 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 2.57862595121731 bayes_pls_golite062009
active transmembrane transporter activity 2.50524643368579 bayes_pls_golite062009
hydrolase activity 2.11429056985835 bayes_pls_golite062009
ATPase activity, coupled 1.96367406225153 bayes_pls_golite062009
nucleoside-triphosphatase activity 1.76379885224229 bayes_pls_golite062009
pyrophosphatase activity 1.69566510056354 bayes_pls_golite062009
ATPase activity 1.69439936736892 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 1.67811565012269 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 1.67577649087358 bayes_pls_golite062009
binding 1.5759873319504 bayes_pls_golite062009
catalytic activity 0.902495165806215 bayes_pls_golite062009
protein binding 0.458389541110755 bayes_pls_golite062009
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