| Protein: | nhr-23 |
| Organism: | Caenorhabditis elegans |
| Length: | 553 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nhr-23.
| Description | E-value | Query Range |
Subject Range |
|
|
320.0 | [0..17] | [550..2] |
|
Region A: Residues: [1-117] |
1 11 21 31 41 51
| | | | | |
1 MQAVEQKLAD ATRTLHAKSS LQPSLSIETP KSKENDESGC ESSNCMFHPH TIKSEPNFCF 60
61 AREFKSVPDD FRIGGGDLQM GNNSKRLTCV IDTNRVDMAG ILPDNMSFRG LPENKSL
|
| Detection Method: |  |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [118-256] |
1 11 21 31 41 51
| | | | | |
1 LVSAQIEVIP CKVCGDKSSG VHYGVITCEG CKGFFRRSQS SIVNYQCPRQ KNCVVDRVNR 60
61 NRCQYCRLKK CIELGMSRDA VKFGRMSKKQ REKVEDEVRM HKELAANGLG YQAIYGDYSP 120
121 PPSHPSYCFD QSMYGHYPS
|
| Detection Method: | |
| Confidence: | 27.39794 |
| Match: | 2a66A |
| Description: | Human Liver Receptor Homologue DNA-Binding Domain (hLRH-1 DBD) in Complex with dsDNA from the hCYP7A1 Promoter |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [257-553] |
1 11 21 31 41 51
| | | | | |
1 GTSTPVNGYS IAVAATPTTP MPQNMYGATP SSTNGTQYVA HQATGGSFPS PQVPEEDVAT 60
61 RVIRAFNQQH SSYTTQHGVC NVDPDCIPHL SRAGGWELFA RELNPLIQAI IEFAKSIDGF 120
121 MNLPQETQIQ LLKGSVFELS LVFAAMYYNV DAQAVCGERY SVPFACLIAE DDAEMQLIVE 180
181 VNNTLQEIVH LQPHQSELAL LAAGLILEQV SSSHGIGILD TATIATAETL KNALYQSVMP 240
241 RIGCMEDTIH RIQDVETRIR QTARLHQEAL QNFRMSDPTS SEKLPALYKE LFTADRP
|
| Detection Method: | |
| Confidence: | 56.154902 |
| Match: | 1lbdA |
| Description: | LIGAND-BINDING DOMAIN OF THE HUMAN NUCLEAR RECEPTOR RXR-ALPHA |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 5.53061626347066 | bayes_pls_golite062009 |
| DNA binding | 4.92165988569962 | bayes_pls_golite062009 |
| nucleic acid binding | 4.78024150262074 | bayes_pls_golite062009 |
| transcription activator activity | 4.53302455129434 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 4.11614358606713 | bayes_pls_golite062009 |
| transcription factor activity | 4.0914094580319 | bayes_pls_golite062009 |
| ligand-dependent nuclear receptor activity | 3.89763470197726 | bayes_pls_golite062009 |
| binding | 3.85318710398432 | bayes_pls_golite062009 |
| transcription repressor activity | 3.83878598697109 | bayes_pls_golite062009 |
| protein binding | 3.21524787168952 | bayes_pls_golite062009 |
| transcription factor binding | 2.68044489404568 | bayes_pls_golite062009 |
| receptor activity | 2.62895787183554 | bayes_pls_golite062009 |
| ecdysteroid hormone receptor activity | 2.42118322312622 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.38308182853979 | bayes_pls_golite062009 |
| steroid hormone receptor activity | 2.30195937604451 | bayes_pls_golite062009 |
| molecular transducer activity | 2.04709877069886 | bayes_pls_golite062009 |
| signal transducer activity | 2.04709877069886 | bayes_pls_golite062009 |
| transcription cofactor activity | 1.73827483890179 | bayes_pls_golite062009 |
| nuclear hormone receptor binding | 1.60419100774741 | bayes_pls_golite062009 |
| retinoic acid receptor binding | 1.59968001933699 | bayes_pls_golite062009 |
| retinoid X receptor binding | 1.45560845709347 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.34794228300778 | bayes_pls_golite062009 |
| transcription coactivator activity | 1.23834725221597 | bayes_pls_golite062009 |
| transcription corepressor activity | 0.995333369475571 | bayes_pls_golite062009 |
| retinoic acid receptor activity | 0.853869057774515 | bayes_pls_golite062009 |
| protein dimerization activity | 0.797229273848179 | bayes_pls_golite062009 |
| hormone receptor binding | 0.74373733735458 | bayes_pls_golite062009 |
| promoter binding | 0.58091332905515 | bayes_pls_golite062009 |
| protein N-terminus binding | 0.57701453824007 | bayes_pls_golite062009 |
| thyroid hormone receptor activity | 0.49784404390361 | bayes_pls_golite062009 |
| protein heterodimerization activity | 0.45265806678057 | bayes_pls_golite062009 |
| receptor binding | 0.418843034756825 | bayes_pls_golite062009 |
| ligand-regulated transcription factor activity | 0.202197503742221 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity, enhancer binding | 0.15737167800277 | bayes_pls_golite062009 |
| catalytic activity | 0.106902059021677 | bayes_pls_golite062009 |
