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View Structure Prediction Details

Protein: CE29126
Organism: Caenorhabditis elegans
Length: 580 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE29126.

Description E-value Query
Range
Subject
Range
gi|73976777 - gi|73976777|ref|XP_857296.1| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 1 ...
290.0 [0..77] [578..4]

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Predicted Domain #1
Region A:
Residues: [1-160]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTDGSMDIDA MLEGGLEMAK NDRSQSRQRS PARSNRSRSR SKDRKSSSRR SRSRSRDRRG  60
   61 DRGDRRRSRS RSKDRRTTRR RSPSRERRRS RSRDRGAPRR RSRTRSRDRR RSPPRRRDRR 120
  121 TPPRRSPGRR SPPRSRLPGP ERRDVMPFNP RHSPPKNAKL 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [161-366]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ELTAEERDQR TLLIMQIARD TRPRDLEEFF SAVGAVRDVR IITDSRTGRS KGICYVEFWD  60
   61 EESVPLGLAL NGQRLMGAPL QIQRTCAERN RAANSSVAST LGFVAPGNKG PTHVLVENLH 120
  121 PKIDEKMIRD IFESFGRIEK IDLEVDSNRE NRGFATITFR NADDAQKSCE QLNNFELAGR 180
  181 CIRLSIKQES QAPAVKKEEA SIHQRS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 42.221849
Match: 1cvjA
Description: Poly(A)-binding protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 6.73097473547076 bayes_pls_golite062009
6.62953239642182 bayes_pls_golite062009
mRNA binding 5.29759606920196 bayes_pls_golite062009
nucleic acid binding 4.92126426323641 bayes_pls_golite062009
binding 3.64400841800969 bayes_pls_golite062009
snRNA binding 3.28448936696877 bayes_pls_golite062009
poly-pyrimidine tract binding 3.11990160533699 bayes_pls_golite062009
single-stranded RNA binding 2.93798024346416 bayes_pls_golite062009
U1 snRNA binding 2.26303528058407 bayes_pls_golite062009
transcription regulator activity 1.92450390013691 bayes_pls_golite062009
DNA binding 1.8021593476478 bayes_pls_golite062009
structural molecule activity 1.29928829870122 bayes_pls_golite062009
transcription factor activity 1.15127506309683 bayes_pls_golite062009
protein binding 1.12215421354121 bayes_pls_golite062009
mRNA 3'-UTR binding 0.591700155096213 bayes_pls_golite062009
sequence-specific DNA binding 0.383589644462932 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [367-580]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LDDVGDRQGF SLGAGGRQQL MAKLAQGTGS GMELTASAQM AAQHAGHSQI PSIATQCFLL  60
   61 SNMFDPSKET EPAWDHDIRE DVIEQCLAHG GALHVFVDKG SEQGNVYVKC PSIVIAHQAV 120
  121 SALHGRWFSG KVITANYVPV NSYHDLFPDA VHARIVLTTR GAAPVVPIVP MVPVVPPQGI 180
  181 ANGYGAYGMM APAHGAPPPP PPQQQGQYGG YGRY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.69897
Match: 2ditA
Description: No description for 2ditA was found.

Predicted functions:

Term Confidence Notes
RNA binding 6.73097473547076 bayes_pls_golite062009
6.62953239642182 bayes_pls_golite062009
mRNA binding 5.29759606920196 bayes_pls_golite062009
nucleic acid binding 4.92126426323641 bayes_pls_golite062009
binding 3.64400841800969 bayes_pls_golite062009
snRNA binding 3.28448936696877 bayes_pls_golite062009
poly-pyrimidine tract binding 3.11990160533699 bayes_pls_golite062009
single-stranded RNA binding 2.93798024346416 bayes_pls_golite062009
U1 snRNA binding 2.26303528058407 bayes_pls_golite062009
transcription regulator activity 1.92450390013691 bayes_pls_golite062009
DNA binding 1.8021593476478 bayes_pls_golite062009
structural molecule activity 1.29928829870122 bayes_pls_golite062009
transcription factor activity 1.15127506309683 bayes_pls_golite062009
protein binding 1.12215421354121 bayes_pls_golite062009
mRNA 3'-UTR binding 0.591700155096213 bayes_pls_golite062009
sequence-specific DNA binding 0.383589644462932 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle