| Protein: | pkc-1 |
| Organism: | Caenorhabditis elegans |
| Length: | 707 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for pkc-1.
| Description | E-value | Query Range |
Subject Range |
|
|
614.0 | [0..1] | [707..1] |
|
Region A: Residues: [1-137] |
1 11 21 31 41 51
| | | | | |
1 MLFTGTVRVR VLEARQLRPT EWSRRFRQDE AATAAIDSYV NVDWDEYHIG KTQVRPKTNE 60
61 PRWNEEFTAS GVHQGKAIGF SVFHSCVMPP DDFVANTRIA FDQLKIGSAN DIWVDLEPHG 120
121 QLHVVVEMHG TNVEDVH
|
| Detection Method: |  |
| Confidence: | 31.154902 |
| Match: | 1gmiA |
| Description: | Domain from protein kinase C epsilon |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| calcium-dependent phospholipid binding | 4.44639260287301 | bayes_pls_golite062009 |
| binding | 2.77482286467294 | bayes_pls_golite062009 |
| phospholipid binding | 2.74013385479058 | bayes_pls_golite062009 |
| protein binding | 2.38962673708753 | bayes_pls_golite062009 |
| neurexin binding | 1.99616093461872 | bayes_pls_golite062009 |
| lipid binding | 1.47484095830847 | bayes_pls_golite062009 |
| receptor activity | 1.33810899162617 | bayes_pls_golite062009 |
| transporter activity | 1.2628067945512 | bayes_pls_golite062009 |
| signal transducer activity | 1.10701462579828 | bayes_pls_golite062009 |
| molecular transducer activity | 1.10701462579828 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.816751946072324 | bayes_pls_golite062009 |
| syntaxin-1 binding | 0.655976398483981 | bayes_pls_golite062009 |
| GTPase regulator activity | 0.640971174993756 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 0.632268019524323 | bayes_pls_golite062009 |
| hydrolase activity | 0.501946993060588 | bayes_pls_golite062009 |
| SNARE binding | 0.3731056408292 | bayes_pls_golite062009 |
| profilin binding | 0.32399339703241 | bayes_pls_golite062009 |
| calmodulin binding | 0.26906635924237 | bayes_pls_golite062009 |
| enzyme regulator activity | 0.24011514942644 | bayes_pls_golite062009 |
| small GTPase regulator activity | 0.0536444296215369 | bayes_pls_golite062009 |
|
Region A: Residues: [138-247] |
1 11 21 31 41 51
| | | | | |
1 SHNKTRVFKE RTNAFNDRQR RGAMRRKIHE VTGHKFMALF LRQPTFCAHC KEFIWGIGKQ 60
61 GYQCQICTVV VHKRCHEDVV WKCPGNKADA VEELGKEIQE TGAGRFNINM
|
| Detection Method: | |
| Confidence: | 12.522879 |
| Match: | 1xa6A |
| Description: | Crystal Structure of the Human Beta2-Chimaerin |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| general RNA polymerase II transcription factor activity | 3.34605625047342 | bayes_pls_golite062009 |
| transcription regulator activity | 2.86705824967236 | bayes_pls_golite062009 |
| binding | 2.79128751898373 | bayes_pls_golite062009 |
| GTPase regulator activity | 2.70614727793157 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 2.68579854252375 | bayes_pls_golite062009 |
| protein binding | 2.34145982999922 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 2.10625597744594 | bayes_pls_golite062009 |
| DNA binding | 2.06132216820898 | bayes_pls_golite062009 |
| guanyl-nucleotide exchange factor activity | 2.06038764955701 | bayes_pls_golite062009 |
| kinase activity | 2.03632850156074 | bayes_pls_golite062009 |
| enzyme regulator activity | 1.9750017471254 | bayes_pls_golite062009 |
| small GTPase regulator activity | 1.95738547986197 | bayes_pls_golite062009 |
| nucleic acid binding | 1.91441035614579 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.8531437045627 | bayes_pls_golite062009 |
| protein kinase activity | 1.62921423829738 | bayes_pls_golite062009 |
| transferase activity | 1.4550521488922 | bayes_pls_golite062009 |
| transcription factor activity | 1.39657429296564 | bayes_pls_golite062009 |
| signal transducer activity | 1.25507073225414 | bayes_pls_golite062009 |
| molecular transducer activity | 1.25507073225414 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 1.10685156896266 | bayes_pls_golite062009 |
| Ras GTPase activator activity | 1.09070479183477 | bayes_pls_golite062009 |
| Ras guanyl-nucleotide exchange factor activity | 0.958295643211986 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.956859696337723 | bayes_pls_golite062009 |
| GTPase activator activity | 0.717730683557543 | bayes_pls_golite062009 |
| kinase binding | 0.494958567742569 | bayes_pls_golite062009 |
| enzyme activator activity | 0.298334474872045 | bayes_pls_golite062009 |
| catalytic activity | 0.194464246602439 | bayes_pls_golite062009 |
|
Region A: Residues: [248-625] |
1 11 21 31 41 51
| | | | | |
1 PHRFSVHSYK RPTFCDHCGS MLYGLINQGL QCSTCKLNVH KRCQRNVANN CGINAKQMAA 60
61 ELAQLGLTGD KMSIRSKKKP SIMTDTSTDI SGSSNSENSG YLQQISEDDS GTTSSRSASK 120
121 VPGGTLSIHD FTFMKVLGKG SFGKVMLAER KGTDEVYAIK ILKKDVIVQD DDVECTMCEK 180
181 RILSLAAKHP FLTALHSSFQ TSDRLFFVME YVNGGDLMFQ IQRARKFDES RARFYAAEVT 240
241 CALQFLHRND VIYRDLKLDN ILLDAEGHCR LADFGMCKEG INKDNLTSTF CGTPDYIAPE 300
301 ILQEMEYGVS VDWWALGVLM YEMMAGQPPF EADNEDDLFE AILNDDVLYP VWLSKEAVNI 360
361 LKAFMTKNAG KRLGCVVS
|
| Detection Method: | |
| Confidence: | 36.0 |
| Match: | 2ozoA |
| Description: | No description for 2ozoA was found. |
|
Region A: Residues: [626-707] |
1 11 21 31 41 51
| | | | | |
1 QGGEDAIRAH PFFREIDWDA LESRQVKPPF KPKIKSKRDA NNFDSDFTKE EPVLTPSDPA 60
61 VVRAINQDEF RGFSFINPHF TY
|
| Detection Method: | |
| Confidence: | 88.39794 |
| Match: | 2i0eA |
| Description: | No description for 2i0eA was found. |
