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View Structure Prediction Details

Protein: CE28755
Organism: Caenorhabditis elegans
Length: 383 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE28755.

Description E-value Query
Range
Subject
Range
gi|55740406 - gi|55740406|gb|AAV63979.1| cathepsin L1 precursor [Artemia parthenogenetica]
321.0 [0..55] [382..4]

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Predicted Domain #1
Region A:
Residues: [1-383]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVSATVFNEE QKPCKAVDDR IEIPVETLIK NRKYPNGNSD LSYVLTQLFS GLVLLTMLIL  60
   61 LSFFVFQRLN HKMENLKHEQ MFNDFILKFD RKYTSVEEFE YRYQIFLRNV IEFEAEEERN 120
  121 LGLDLDVNEF TDWTDEELQK MVQENKYTKY DFDTPKFEGS YLETGVIRPA SIDWREQGKL 180
  181 TPIKNQGQCG SCWAFATVAS VEAQNAIKKG KLVSLSEQEM VDCDGRNNGC SGGYRPYAMK 240
  241 FVKENGLESE KEYPYSALKH DQCFLKENDT RVFIDDFRML SNNEEDIANW VGTKGPVTFG 300
  301 MNVVKAMYSY RSGIFNPSVE DCTEKSMGAH ALTIIGYGGE GESAYWIVKN SWGTSWGASG 360
  361 YFRLARGVNS CGLANTVVAP IIN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 80.522879
Match: 1by8A
Description: (Pro)cathepsin K
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 4.90619850296986 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 4.64381885397949 bayes_pls_golite062009
endopeptidase activity 3.75054525912786 bayes_pls_golite062009
hydrolase activity 3.74079711298952 bayes_pls_golite062009
cysteine-type peptidase activity 2.71117522993364 bayes_pls_golite062009
cysteine-type endopeptidase activity 1.95802900199539 bayes_pls_golite062009
binding 1.29265216891074 bayes_pls_golite062009
catalytic activity 1.05972260874031 bayes_pls_golite062009
protein binding 0.774177093888744 bayes_pls_golite062009
small conjugating protein-specific protease activity 0.649171767629235 bayes_pls_golite062009
thiolester hydrolase activity 0.59115205419466 bayes_pls_golite062009
kininogen binding 0.41283715939055 bayes_pls_golite062009
ubiquitin-specific protease activity 0.0101379718864654 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle