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View Structure Prediction Details

Protein: CE27708
Organism: Caenorhabditis elegans
Length: 408 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE27708.

Description E-value Query
Range
Subject
Range
gi|73976781 - gi|73976781|ref|XP_857374.1| PREDICTED: similar to Polyadenylate-binding protein 4 (Poly(A)-binding ...
306.0 [0..4] [405..59]

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Predicted Domain #1
Region A:
Residues: [1-214]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFFNPPANS NHGYNDDVNT GYNARMHSKL AEREGFHLGN GSDEPRTLYV GNLDSTVTED  60
   61 FIATLFNQIG SVTKTKVIFD GSNDPYAFVE FSDHGQASQA LQTMNKRLLL DREMKVNWAV 120
  121 EPGQQQSKID TTRHFHVFVG DLSSEVDNQK LREAFQPFGD VSDAKVIRDT NTTKSKGYGF 180
  181 VSYPKREEAE RAIEQMNGQW LGRRTIRTNW ATRK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 46.154902
Match: 1ha1A
Description: HNRNP A1 (RBD1,2) FROM HOMO SAPIENS
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 6.73097473547076 bayes_pls_golite062009
6.62953239642182 bayes_pls_golite062009
mRNA binding 5.29759606920196 bayes_pls_golite062009
nucleic acid binding 4.92126426323641 bayes_pls_golite062009
snRNA binding 4.06596327298973 bayes_pls_golite062009
binding 3.64400841800969 bayes_pls_golite062009
poly-pyrimidine tract binding 3.11990160533699 bayes_pls_golite062009
U1 snRNA binding 3.02511982045347 bayes_pls_golite062009
single-stranded RNA binding 2.93798024346416 bayes_pls_golite062009
transcription regulator activity 2.18211199677674 bayes_pls_golite062009
DNA binding 1.98418556946403 bayes_pls_golite062009
structural molecule activity 1.56454315220334 bayes_pls_golite062009
U2 snRNA binding 1.34078165372485 bayes_pls_golite062009
protein binding 1.12215421354121 bayes_pls_golite062009
transcription factor activity 1.07843408116687 bayes_pls_golite062009
mRNA 3'-UTR binding 0.824614388276642 bayes_pls_golite062009
sequence-specific DNA binding 0.383589644462932 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [215-311]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PGDQEKPSHY NEKSYDEIYN QTSGDNTSVY VGNIASLTED EIRQGFASFG RITEVRIFKM  60
   61 QGYAFVKFDN KDAAAKAIVQ MNNQDVGGQL VRCSWGK

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.88
Match: 1x4gA
Description: Solution structure of RRM domain in Nucleolysin TIAR
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
6.40066880991253 bayes_pls_golite062009
RNA binding 6.32219487559982 bayes_pls_golite062009
mRNA binding 4.87640532914983 bayes_pls_golite062009
nucleic acid binding 4.65259034341669 bayes_pls_golite062009
snRNA binding 3.77997752511163 bayes_pls_golite062009
binding 3.48033873254013 bayes_pls_golite062009
U1 snRNA binding 2.73908382552928 bayes_pls_golite062009
poly-pyrimidine tract binding 2.7133834347239 bayes_pls_golite062009
single-stranded RNA binding 2.55628738360472 bayes_pls_golite062009
transcription regulator activity 2.2045206027152 bayes_pls_golite062009
DNA binding 1.99030664201171 bayes_pls_golite062009
structural molecule activity 1.57342338925793 bayes_pls_golite062009
transcription factor activity 1.09958329302628 bayes_pls_golite062009
U2 snRNA binding 1.09350203162237 bayes_pls_golite062009
protein binding 1.05805521997665 bayes_pls_golite062009
mRNA 3'-UTR binding 0.462558743683805 bayes_pls_golite062009
sequence-specific DNA binding 0.327072171076297 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [312-408]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TGDTGKTPGG SYGYGYGNSS SGGNSQPYSG YGGGGAYGGG QGGGGHGGPG QQQSNANSQY  60
   61 WQYYAQYYNN PQLMQQWSNY WQQQGGAPQQ QNSGGHQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle