| Protein: | nhr-6 |
| Organism: | Caenorhabditis elegans |
| Length: | 619 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nhr-6.
| Description | E-value | Query Range |
Subject Range |
|
|
339.0 | [0..83] | [616..275] |
|
Region A: Residues: [1-249] |
1 11 21 31 41 51
| | | | | |
1 MEQLSIQTDE LQDQFSNCSP ASVDSSYSSC SSVEDEIEIY TRLVRNEEPL RRDFFREMSK 60
61 NSSCSSSFDY GEFGPSSSSR KGSKTTDADL DSLFHSLVET SDQVNTVPKP TKTEVESIPE 120
121 EFEQKPSSSS HRLPSEMNAS ITHIKSELDP TMQAFQMPHN DLFLATAAPH YNPFALSNDF 180
181 MPNPLMPSFT SPFYPQHFPV SDSRRGSQGT TSSSNNTGGT PSPHSSSLPT SPPQLQGFLR 240
241 SFLNPDNLS
|
| Detection Method: |  |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [250-349] |
1 11 21 31 41 51
| | | | | |
1 TPTSFGVPSE TALDADKMCA VCNDRAVCLH YGARTCEGCK GFFKRTVQKN SKYTCAGNKT 60
61 CPIDKRYRSR CQYCRYQKCL EVGMVKEIVR HGSLSGRRGR
|
| Detection Method: | |
| Confidence: | 20.0 |
| Match: | 1ynwB |
| Description: | Crystal Structure of Vitmain D Receptor and 9-cis Retinoic Acid Receptor DNA-Binding Domains Bound to a DR3 Response Element |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [350-619] |
1 11 21 31 41 51
| | | | | |
1 LSSKTKLARS EDQPSPPLPL LALMGKAIED HTNMTVVRQF MQPFDETIAL RILHGELHAT 60
61 KKLLMAMPQI SEIQPADFQI LLSRSFFAIM AIRVANRCGN STDTIMFESG ELFSLNAFPA 120
121 CFQQIIRFMV DKARTFSSLV DWEPQAFAAF IALQFLAGNT EHNVLGLTNK PLVDQVQSTI 180
181 INALKDHCSG SQNKLAKIVR LTQEFDVFHA LGLQALDILY PSHQLPEEFM FLINLTRAPL 240
241 RSTDAPPACG SPVAPSGSSL FNFQMGPAAF
|
| Detection Method: | |
| Confidence: | 66.39794 |
| Match: | 1lbdA |
| Description: | LIGAND-BINDING DOMAIN OF THE HUMAN NUCLEAR RECEPTOR RXR-ALPHA |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 5.53061626347066 | bayes_pls_golite062009 |
| DNA binding | 4.92165988569962 | bayes_pls_golite062009 |
| nucleic acid binding | 4.78024150262074 | bayes_pls_golite062009 |
| transcription activator activity | 4.53302455129434 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 4.11614358606713 | bayes_pls_golite062009 |
| transcription factor activity | 4.0914094580319 | bayes_pls_golite062009 |
| ligand-dependent nuclear receptor activity | 3.89763470197726 | bayes_pls_golite062009 |
| binding | 3.85318710398432 | bayes_pls_golite062009 |
| protein binding | 3.21524787168952 | bayes_pls_golite062009 |
| transcription factor binding | 2.68044489404568 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.38308182853979 | bayes_pls_golite062009 |
| steroid hormone receptor activity | 2.30195937604451 | bayes_pls_golite062009 |
| transcription repressor activity | 2.20686235000733 | bayes_pls_golite062009 |
| receptor activity | 2.07573173722434 | bayes_pls_golite062009 |
| transcription cofactor activity | 1.73827483890179 | bayes_pls_golite062009 |
| nuclear hormone receptor binding | 1.60419100774741 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.34794228300778 | bayes_pls_golite062009 |
| retinoic acid receptor binding | 1.28118886948947 | bayes_pls_golite062009 |
| transcription coactivator activity | 1.23834725221597 | bayes_pls_golite062009 |
| molecular transducer activity | 1.19872119297817 | bayes_pls_golite062009 |
| signal transducer activity | 1.19872119297817 | bayes_pls_golite062009 |
| retinoid X receptor binding | 0.99801784942981 | bayes_pls_golite062009 |
| retinoic acid receptor activity | 0.853869057774515 | bayes_pls_golite062009 |
| protein dimerization activity | 0.797229273848179 | bayes_pls_golite062009 |
| hormone receptor binding | 0.74373733735458 | bayes_pls_golite062009 |
| promoter binding | 0.58091332905515 | bayes_pls_golite062009 |
| protein N-terminus binding | 0.57701453824007 | bayes_pls_golite062009 |
| thyroid hormone receptor activity | 0.49784404390361 | bayes_pls_golite062009 |
| protein heterodimerization activity | 0.45265806678057 | bayes_pls_golite062009 |
| receptor binding | 0.418843034756825 | bayes_pls_golite062009 |
| ligand-regulated transcription factor activity | 0.202197503742221 | bayes_pls_golite062009 |
| lipid binding | 0.164046651023989 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity, enhancer binding | 0.15737167800277 | bayes_pls_golite062009 |
| catalytic activity | 0.106902059021677 | bayes_pls_golite062009 |
