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View Structure Prediction Details

Protein: nuo-5
Organism: Caenorhabditis elegans
Length: 729 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nuo-5.

Description E-value Query
Range		 Subject
Range
gi|78044647, gi|... - gi|78044647|ref|YP_359587.1| NAD-dependent formate dehydrogenase, alpha subunit, selenocysteine-cont...
 623.0 [0..30] [728..2]

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Predicted Domain #1
Region A:
Residues: [1-729] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHRVGGQIVR GVSKAQQKRS LSVAAPAPPK KVEVFIDDKK VLVDPGMTIL QACALVGVDI  60
   61 PRFCYHDRLS IAGNCRMCLV EVEKSVKPVA SCAMPVMNGM KVKTNSDFVK KAREGVMEFM 120
  121 LNNHPLDCPI CDQGGECDLQ DQAMNFGSDR GRLQSRFDGK RALEDKNIGP LVKTVMTRCI 180
  181 QCTRCVRFAN EVAAFPDFGT TGRGQDLQIG TYVEKFFASE LSGNIIDICP VGALTSKQYA 240
  241 FTARPWETRK TESVDVMDAT GSNIVLSHRT GELLRVIPKI NDDINEEWIG DQSRFAVDGL 300
  301 KVQRLLTPMI RGADGQLKPA TWEEALFTVA AKLRETPAEQ KAAVAGGLND VESLVALKDL 360
  361 FNRFNSENVM TEEEFPDVGS GGSDLRSNYV FNDGIASVEN ADAILLVGTN PRFEAPTLNA 420
  421 RIRKSFLYSD VQVGVIGAET ELTYEYDYLG ASAKAIDEIL AGKGDFAKIL SSATTPLIIV 480
  481 GAQALKGEAG AALLGKLQQL ADKLGSGKEV KVLNVLQRWA GQAGALDVGY KAGTAGIRKT 540
  541 PIKFLYLLGA DEGKVTKANL DPSAFVVYQG HHGDAGAEMA DVVLPGAAYT EKEGTYVNTE 600
  601 GRSQRAYPAV SPPGDARVDW KIIRAVSEVS GKSLPYSDLK EIRQRLNEIA PHLVRYRDLE 660
  661 ASPFVKQALQ LAQPTGSIDV DVSPVLRELS DYYQTNVISR YSRSMAQARK AAIENKTNPY 720
  721 AEEPVYARL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 100.0
Match: 2fug3
Description: Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
NADH dehydrogenase activity 8.57020397959255 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH 8.38566609923386 bayes_pls_golite062009
NADH dehydrogenase (ubiquinone) activity 8.21082857163161 bayes_pls_golite062009
NADH dehydrogenase (quinone) activity 7.52220758347541 bayes_pls_golite062009
oxidoreductase activity 7.16286065347789 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor 7.03780998761655 bayes_pls_golite062009
formate dehydrogenase activity 4.68407412780362 bayes_pls_golite062009
4 iron, 4 sulfur cluster binding 3.54243134597505 bayes_pls_golite062009
oxidoreduction-driven active transmembrane transporter activity 3.29174700910768 bayes_pls_golite062009
succinate dehydrogenase activity 3.27019699125535 bayes_pls_golite062009
electron carrier activity 2.86867645862628 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors 2.73204059194206 bayes_pls_golite062009
metal cluster binding 2.57357653703854 bayes_pls_golite062009
iron-sulfur cluster binding 2.57357653703854 bayes_pls_golite062009
nitrate reductase activity 2.20600951698793 bayes_pls_golite062009
catalytic activity 1.93875927205186 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor 1.87673954208357 bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors 1.84836110501265 bayes_pls_golite062009
oxidoreductase activity, acting on other nitrogenous compounds as donors 1.12492792673137 bayes_pls_golite062009
binding 1.0770649921334 bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 0.737415967372169 bayes_pls_golite062009
transition metal ion binding 0.614505320206825 bayes_pls_golite062009
ferrous iron binding 0.599635746381861 bayes_pls_golite062009
cation binding 0.292059992813768 bayes_pls_golite062009
metal ion binding 0.292059992813768 bayes_pls_golite062009
ion binding 0.285849308897776 bayes_pls_golite062009
protein binding 0.128023487683923 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle