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View Structure Prediction Details

Protein: unc-62
Organism: Caenorhabditis elegans
Length: 527 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for unc-62.

Description E-value Query
Range
Subject
Range
unc-62 - homeobox protein status:Confirmed UniProt:Q9N5D6 protein_id:AAF39974.1
344.0 [0..3] [527..40]

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Predicted Domain #1
Region A:
Residues: [1-214]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAQRQFNDGY GPPPGSASAD PASYIADPAA FYNLYTNMGG APTSTPMMHH EMGEAMKRDK  60
   61 ESIYAHPLYP LLVLLFEKCE LATSTPRDTS RDGSTSSDVC SSASFKDDLN EFVRHTQENA 120
  121 DKQYYVPNPQ LDQIMLQSIQ MLRFHLLELE KVHELCDNFC NRYVVCLKGK MPLDIVGDER 180
  181 ASSSQPPMSP GSMGHLGHSS SPSMAGGATP MHYP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [215-304]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPYEPQSVPL PENAGVMGGH PMEGSSMAYS MAGMAAAAAS SSSSSNQAGD HPLANGGTLH  60
   61 STAGASQTLL PIAVSSPSTC SSGGLRQDST 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [305-431]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLSGETPMGH ANGNSMDSIS EAGDEFSVCG SNDDGRDSVL SDSANGSQNG KRKVPKVFSK  60
   61 EAITKFRAWL FHNLTHPYPS EEQKKQLAKE TGLTILQVNN WFINARRRIV QPMIDQNNRA 120
  121 GRSGQMN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.154902
Match: 1b72B
Description: pbx1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 1.62959077995642 bayes_pls_golite062009
binding 1.48969201384255 bayes_pls_golite062009
DNA binding 1.2137926921894 bayes_pls_golite062009
nucleic acid binding 1.02805703044131 bayes_pls_golite062009
transcription factor activity 0.89626527070971 bayes_pls_golite062009
sequence-specific DNA binding 0.06790788268651 bayes_pls_golite062009
protein binding 0.012115247005138 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [432-527]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VCKNRRRNRS EQSPGPSPDS GSDSGANYSP DPSSLAASTA MPYPAEFYMQ RTMPYGGFPS  60
   61 FTNPAMPFMN PMMGFQVAPT VDALSQQWVD LSAPHE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle