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View Structure Prediction Details

Protein: unc-62
Organism: Caenorhabditis elegans
Length: 564 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for unc-62.

Description E-value Query
Range
Subject
Range
unc-62 - status:Confirmed UniProt:Q9N5D6 protein_id:AAO61421.1
416.0 [0..1] [564..1]

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Predicted Domain #1
Region A:
Residues: [1-87]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGDSKVWAH ASADTWAVQN GISTYDLDTS SIKREKRDHN EQFNDGYGPP PGSASADPAS  60
   61 YIADPAAFYN LYTNMGGAPT STPMMHH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [88-323]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EMGEAMKRDK ESIYAHPLYP LLVLLFEKCE LATSTPRDTS RDGSTSSDVC SSASFKDDLN  60
   61 EFVRHTQENA DKQYYVPNPQ LDQIMLQSIQ MLRFHLLELE KVHELCDNFC NRYVVCLKGK 120
  121 MPLDIVGDER ASSSQPPMSP GSMGHLGHSS SPSMAGGATP MHYPPPYEPQ SVPLPENAGV 180
  181 MGGHPMEGSS MAYSMAGMAA AAASSSSSSN QAGDHPLANG GTLHSTAGAS QTLLPI

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [324-391]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AVSSPSTCSS GGLRQDSTPL SGETPMGHAN GNSMDSISEA GDEFSVCGSN DDGRDSVLSD  60
   61 SANGSQNG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [392-470]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KRKVPKVFSK EAITKFRAWL FHNLTHPYPS EEQKKQLAKE TGLTILQVNN WFINARRRIV  60
   61 QPMIDQNNRA GRSGQMNVC

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.69897
Match: 1x2nA
Description: Solution structure of the homeobox domain of human homeobox protein PKNOX1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 1.62959077995642 bayes_pls_golite062009
binding 1.48969201384255 bayes_pls_golite062009
DNA binding 1.2137926921894 bayes_pls_golite062009
nucleic acid binding 1.02805703044131 bayes_pls_golite062009
transcription factor activity 0.89626527070971 bayes_pls_golite062009
sequence-specific DNA binding 0.06790788268651 bayes_pls_golite062009
protein binding 0.012115247005138 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [471-564]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KNRRRNRSEQ SPGPSPDSGS DSGANYSPDP SSLAASTAMP YPAEFYMQRT MPYGGFPSFT  60
   61 NPAMPFMNPM MGFQVAPTVD ALSQQWVDLS APHE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


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