YRC Public Data Repository - Protein Structure Prediction

Protein:	pbs-7
Organism:	Caenorhabditis elegans
Length:	236 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for pbs-7.

Description	E-value	Query Range	Subject Range
PSA_PYRAB - Proteasome subunit alpha OS=Pyrococcus abyssi (strain GE5 / Orsay) GN=psmA PE=3 SV=1 PSMA_PYRAB - Proteasome subunit alpha OS=Pyrococcus abyssi GN=psmA PE=3 SV=1	210.0	[0..6]	[226..25]
PSA_PYRFU - Proteasome subunit alpha OS=Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) GN=p... PSMA_PYRFU - Proteasome subunit alpha OS=Pyrococcus furiosus GN=psmA PE=3 SV=1	208.0	[0..6]	[226..25]
PSA_PYRHO - Proteasome subunit alpha OS=Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC ... PSMA_PYRHO - Proteasome subunit alpha OS=Pyrococcus horikoshii GN=psmA PE=3 SV=1	206.0	[0..6]	[226..25]
gi\|44980444 - gi\|44980444\|gb\|AAS50377.1\| AAR012Cp [Ashbya gossypii ATCC 10895] gi\|45184835, gi\|... - gi\|45184835\|ref\|NP_982553.1\| AAR012Cp [Ashbya gossypii ATCC 10895], gi\|44980444\|gb\|AAS50377.1\| AAR01...	203.0	[0..6]	[236..19]
gi\|50304213, gi\|... - gi\|50304213\|ref\|XP_452056.1\| unnamed protein product [Kluyveromyces lactis], gi\|49641188\|emb\|CAH0244... gi\|49641188 - gi\|49641188\|emb\|CAH02449.1\| KLLA0B11836p [Kluyveromyces lactis]	201.0	[0..6]	[235..19]
gi\|3114286, gi\|2... - gi\|99032218\|pdb\|2FAK\|Q Chain Q, Crystal Structure Of Salinosporamide A In Complex With The Yeast 20s...	201.0	[0..6]	[236..17]
gi\|116283481 - gi\|116283481\|gb\|AAH14999.1\| PSMA7 protein [Homo sapiens]	200.0	[0..6]	[234..18]
gi\|7435881 - pir\|\|D69191 proteasome, alpha subunit - Methanobacterium thermoautotrophicum (strain Delta H) PSA_METTH - Proteasome subunit alpha OS=Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / J...	200.0	[0..6]	[236..24]
gi\|148229628, gi... - gi\|37589390\|gb\|AAH59335.1\| MGC69086 protein [Xenopus laevis], gi\|148229628\|ref\|NP_001080028.1\| low m...	200.0	[0..16]	[234..65]

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Predicted Domain #1

Region A:
Residues: [1-236]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNAHDEVQRT LNPTCTGTSV IALQYKTGVV VLTDRVVSYG KMARYKNVSR QYKVNDNVLI  60
   61 AFGGDHADFH WLQNVIERQV LLWKRFDQDI GPKALHGYLT SLLYAKRCKM NPVWNTLVVA 120
  121 GVEEEEKNNK ETSTPFIGVI TQKGCAYQVK HIATGLGAFL LNQAVEDEWR KKGEDLSREE 180
  181 AEAVLRKSLE LTLYHDCVAD NEFEIGRVDA TEGVVLGKEE KIIGDWSIAE TNCQYE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	36.154902
Match:	1iruN
Description:	Proteasome beta subunit (catalytic)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
endopeptidase activity	6.91642761177919	bayes_pls_golite062009
peptidase activity	6.84511694091156	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	6.5973571808298	bayes_pls_golite062009
hydrolase activity	4.47652590304822	bayes_pls_golite062009
threonine-type endopeptidase activity	2.98214579292788	bayes_pls_golite062009
threonine-type peptidase activity	2.98214579292788	bayes_pls_golite062009
catalytic activity	1.19663085909195	bayes_pls_golite062009
binding	0.982918122186083	bayes_pls_golite062009
nucleic acid binding	0.448212653390607	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: