YRC Public Data Repository - Protein Structure Prediction

Protein:	gpc-2
Organism:	Caenorhabditis elegans
Length:	62 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gpc-2.

Description	E-value	Query Range	Subject Range
gi\|109506258 - gi\|109506258\|ref\|XP_001053747.1\| PREDICTED: similar to Guanine nucleotide-binding protein G(I)/G(S)/...	98.0	[0..2]	[62..222]
GBG7_MOUSE - Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 OS=Mus musculus GN=Gng7 PE=1 SV=2 gi\|117616394 - gi\|117616394\|gb\|ABK42215.1\| G protein gamma 7 [synthetic construct]	97.0	[0..3]	[62..7]
tr\|G3V2N0\|G3V2N0... - Guanine nucleotide-binding protein subunit gamma OS=Homo sapiens GN=GNG2 PE=3 SV=1, Tax_Id=9606 Gene... gi\|114653023 - gi\|114653023\|ref\|XP_001158267.1\| PREDICTED: hypothetical protein isoform 2 [Pan troglodytes]	96.0	[0..2]	[62..47]
gi\|50539862, gi\|... - gi\|50539862\|ref\|NP_001002397.1\| guanine nucleotide binding protein (G protein), gamma 7 [Danio rerio...	96.0	[0..3]	[62..7]
GNG7 - guanine nucleotide binding protein (G protein), gamma 7 gi\|109122851 - gi\|109122851\|ref\|XP_001098800.1\| PREDICTED: similar to guanine nucleotide binding protein (G protein... gi\|114674554 - gi\|114674554\|ref\|XP_001152049.1\| PREDICTED: guanine nucleotide binding protein (G protein), gamma 7 ... gi\|208968219 - gi\|208968219\|dbj\|BAG73948.1\| FLJ00058 [synthetic construct]	96.0	[0..3]	[62..7]
gi\|62858615, gi\|... - gi\|89273841\|emb\|CAJ81829.1\| guanine nucleotide binding protein (G protein), gamma 7 [Xenopus tropica...	96.0	[0..3]	[62..7]
gi\|47229899 - gi\|47229899\|emb\|CAG10313.1\| unnamed protein product [Tetraodon nigroviridis]	96.0	[0..3]	[62..7]
gi\|91084499 - gi\|91084499\|ref\|XP_972123.1\| PREDICTED: similar to Guanine nucleotide-binding protein gamma-e subuni...	95.0	[0..1]	[62..293]

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Predicted Domain #1

Region A:
Residues: [1-62]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDKSDMQRTV DSLRSQLNIE RTPITVSAAE LRRFTESQED PLVNPIDKKV NPWAEKSKCS  60
   61 ML

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	20.0
Match:	1xhmB
Description:	The Crystal Structure of a Biologically Active Peptide (SIGK) Bound to a G Protein Beta:Gamma Heterodimer
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
GTPase activity	6.01646376999889	bayes_pls_golite062009
angiotensin receptor binding	2.59868793911346	bayes_pls_golite062009
type 1 angiotensin receptor binding	2.59868793911346	bayes_pls_golite062009
G-protein-coupled receptor binding	1.93225355053758	bayes_pls_golite062009
nucleoside-triphosphatase activity	1.86638084591699	bayes_pls_golite062009
pyrophosphatase activity	1.79571290781105	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	1.77742639118775	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	1.77512507657227	bayes_pls_golite062009
signal transducer activity	1.75801578312445	bayes_pls_golite062009
molecular transducer activity	1.75801578312445	bayes_pls_golite062009
binding	1.25375089530994	bayes_pls_golite062009
hydrolase activity	0.692793543292009	bayes_pls_golite062009
protein binding	0.399162858691971	bayes_pls_golite062009
receptor binding	0.38304823982539	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: