| Protein: | nhr-3 |
| Organism: | Caenorhabditis elegans |
| Length: | 463 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nhr-3.
| Description | E-value | Query Range |
Subject Range |
|
|
292.0 | [0..3] | [460..9] |
|
Region A: Residues: [1-126] |
1 11 21 31 41 51
| | | | | |
1 MTDTQSPFSF AAALLQCGSP GQTFSMESLL KPELGEYSPS GENGIDGEES TICSVCCDEA 60
61 SGRHYGVVAC FGCKGFFRRT VRAGKNYVCR YSKKCRIDKA GRNVCRSCRF QKCLEVGMEP 120
121 DAIRPD
|
| Detection Method: |  |
| Confidence: | 23.69897 |
| Match: | 2a66A |
| Description: | Human Liver Receptor Homologue DNA-Binding Domain (hLRH-1 DBD) in Complex with dsDNA from the hCYP7A1 Promoter |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [127-463] |
1 11 21 31 41 51
| | | | | |
1 RDKTGRQKNP RRNTEGSIKK VSVGSILGDL PCLNKFKDDS DDAATSPSSR ADSAPMDLRP 60
61 SFIDESVLTT LTEIENIVIQ LQDNFETNQQ SLPPMGEAIT KPSLIAARTL LNFNGAKGVA 120
121 DANCVSSNLR RMIVFTFDYI NTLRPIADLH PSEKLVIARS IISPFCILFC GYQSVAIEAP 180
181 EHDSIYLPSG HKLPASQLLF TKDSDQKKYI LLENKADNVR RNMTEMIIQQ LRRLNVTKTE 240
241 MVALKAIMAL DHNVKGLSAE SCELLVVARE SVQNALFSHL IATFGTAEAT SRFAHLLLLI 300
301 ASATRVAYSL SSFFQLSRDV NYEIDYVLEE LLFLDRI
|
| Detection Method: | |
| Confidence: | 30.69897 |
| Match: | 1ilgA |
| Description: | Pregnane x receptor, PXR |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 5.53061626347066 | bayes_pls_golite062009 |
| DNA binding | 4.92165988569962 | bayes_pls_golite062009 |
| nucleic acid binding | 4.78024150262074 | bayes_pls_golite062009 |
| transcription activator activity | 4.53302455129434 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 4.11614358606713 | bayes_pls_golite062009 |
| transcription factor activity | 4.0914094580319 | bayes_pls_golite062009 |
| ligand-dependent nuclear receptor activity | 3.89763470197726 | bayes_pls_golite062009 |
| binding | 3.85318710398432 | bayes_pls_golite062009 |
| protein binding | 3.21524787168952 | bayes_pls_golite062009 |
| transcription factor binding | 2.68044489404568 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.38308182853979 | bayes_pls_golite062009 |
| steroid hormone receptor activity | 2.30195937604451 | bayes_pls_golite062009 |
| transcription repressor activity | 2.20686235000733 | bayes_pls_golite062009 |
| receptor activity | 2.07573173722434 | bayes_pls_golite062009 |
| transcription cofactor activity | 1.73827483890179 | bayes_pls_golite062009 |
| nuclear hormone receptor binding | 1.60419100774741 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.34794228300778 | bayes_pls_golite062009 |
| retinoic acid receptor binding | 1.28118886948947 | bayes_pls_golite062009 |
| transcription coactivator activity | 1.23834725221597 | bayes_pls_golite062009 |
| molecular transducer activity | 1.19872119297817 | bayes_pls_golite062009 |
| signal transducer activity | 1.19872119297817 | bayes_pls_golite062009 |
| retinoid X receptor binding | 0.99801784942981 | bayes_pls_golite062009 |
| retinoic acid receptor activity | 0.853869057774515 | bayes_pls_golite062009 |
| protein dimerization activity | 0.797229273848179 | bayes_pls_golite062009 |
| hormone receptor binding | 0.74373733735458 | bayes_pls_golite062009 |
| promoter binding | 0.58091332905515 | bayes_pls_golite062009 |
| protein N-terminus binding | 0.57701453824007 | bayes_pls_golite062009 |
| thyroid hormone receptor activity | 0.49784404390361 | bayes_pls_golite062009 |
| protein heterodimerization activity | 0.45265806678057 | bayes_pls_golite062009 |
| receptor binding | 0.418843034756825 | bayes_pls_golite062009 |
| ligand-regulated transcription factor activity | 0.202197503742221 | bayes_pls_golite062009 |
| lipid binding | 0.164046651023989 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity, enhancer binding | 0.15737167800277 | bayes_pls_golite062009 |
| catalytic activity | 0.106902059021677 | bayes_pls_golite062009 |
