| Protein: | CE18278 |
| Organism: | Caenorhabditis elegans |
| Length: | 591 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE18278.
| Description | E-value | Query Range |
Subject Range |
|
|
416.0 | [0..5] | [565..775] |
|
Region A: Residues: [1-95] |
1 11 21 31 41 51
| | | | | |
1 MQRRKGTRGN SQDDQQASRR LAKKPSDEKV DEKDKKKGGV LKRLGFLLHN EKKEEVGSTQ 60
61 KRRKPKRGTE RKRACSHPVW NPDKKIHFNN EKTHA
|
| Detection Method: |  |
| Confidence: | 71.0 |
| Match: | 2shpA |
| Description: | Tyrosine phosphatase; Tyrosine phoshatase shp-2 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| insulin receptor binding | 3.48393497211158 | bayes_pls_golite062009 |
| protein binding | 3.19631993182765 | bayes_pls_golite062009 |
| binding | 3.12724619324809 | bayes_pls_golite062009 |
| phosphoric ester hydrolase activity | 2.76609604594837 | bayes_pls_golite062009 |
| phosphatase activity | 2.39617614358425 | bayes_pls_golite062009 |
| phosphoprotein phosphatase activity | 2.32814368667748 | bayes_pls_golite062009 |
| hydrolase activity, acting on ester bonds | 2.22704087268457 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.85015570449703 | bayes_pls_golite062009 |
| kinase activity | 1.78069536883109 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.59739467025045 | bayes_pls_golite062009 |
| protein kinase activity | 1.4654611643382 | bayes_pls_golite062009 |
| transcription regulator activity | 1.38649262176488 | bayes_pls_golite062009 |
| molecular adaptor activity | 1.33740973673697 | bayes_pls_golite062009 |
| nucleic acid binding | 1.28138694351561 | bayes_pls_golite062009 |
| SH3/SH2 adaptor activity | 1.2323381312171 | bayes_pls_golite062009 |
| transferase activity | 1.19152443245584 | bayes_pls_golite062009 |
| DNA binding | 1.17144894382542 | bayes_pls_golite062009 |
| phosphoinositide 3-kinase regulator activity | 1.03150090191995 | bayes_pls_golite062009 |
| molecular transducer activity | 0.999269271132931 | bayes_pls_golite062009 |
| signal transducer activity | 0.999269271132931 | bayes_pls_golite062009 |
| insulin-like growth factor receptor binding | 0.950445630788802 | bayes_pls_golite062009 |
| protein binding, bridging | 0.83823250804321 | bayes_pls_golite062009 |
| protein phosphorylated amino acid binding | 0.649814096718101 | bayes_pls_golite062009 |
| transcription factor activity | 0.573315212617741 | bayes_pls_golite062009 |
| receptor binding | 0.460399756639525 | bayes_pls_golite062009 |
| phosphotyrosine binding | 0.311079584914389 | bayes_pls_golite062009 |
| insulin receptor substrate binding | 0.29798436765753 | bayes_pls_golite062009 |
| protein tyrosine phosphatase activity | 0.251558977399574 | bayes_pls_golite062009 |
| protein complex binding | 0.19242065162232 | bayes_pls_golite062009 |
| phosphoprotein binding | 0.16798254471727 | bayes_pls_golite062009 |
| kinase regulator activity | 0.10704587503284 | bayes_pls_golite062009 |
|
Region A: Residues: [96-489] |
1 11 21 31 41 51
| | | | | |
1 IIPLKGDPLS DVQKKVFFKF ASDAVKKNPP EYSVEFMTKV KPYPGQPMER KIFDANPTKN 60
61 RYKDVVCNDI TRVILSDGGD GDYIHANYVN GLNAPFILTQ GATAATVIDF WRMVVHTKTA 120
121 YIVMLCEVME DGKAKCAQYY PEKAGEAMTF GAWTILCSLE DDKDANIIKR TLSVRNVDNG 180
181 KEHILKHLHT KSWPDRCVPN STMALLRMLY IVRTASGPVT VHCSAGIGRT GTFVAIEACL 240
241 QILTDGKELD LLGTCRALRN SRAGSIQVDI QYMALVQILI NYGKDNGYWD DSDLDDRVEL 300
301 LTWNIQQFIQ TRGKVDHVPT TPSTPALNII PADAKPVPVV PKEATPHHSP AEKAQECMEK 360
361 ICEKILKPIK KDKECKEHKS PKTEHPKECK DHPL
|
| Detection Method: | |
| Confidence: | 107.0 |
| Match: | 2fh7A |
| Description: | Crystal structure of the phosphatase domains of human PTP SIGMA |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [490-591] |
1 11 21 31 41 51
| | | | | |
1 PLETRSSSED GPDMEDQKTQ ATQKVEIKEE TAAQNDNISM ISLPNEPLLS IPVVRKNSKD 60
61 GNKDSCDTKE SKETKGHEKK NSKEGNFKLV KKQSANRSQY FL
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
