YRC Public Data Repository - Protein Structure Prediction

Protein:	pbs-2
Organism:	Caenorhabditis elegans
Length:	277 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for pbs-2.

Description	E-value	Query Range	Subject Range
gi\|187032980, gi... - gi\|39592394\|emb\|CAE63471.1\| Hypothetical protein CBG07938 [Caenorhabditis briggsae], gi\|187032980\|em...	250.0	[0..1]	[277..1]
gi\|12833090 - gi\|12833090\|dbj\|BAB22385.1\| unnamed protein product [Mus musculus]	243.0	[0..12]	[276..5]
PSB7_RAT - Proteasome subunit beta type-7 OS=Rattus norvegicus GN=Psmb7 PE=1 SV=1	240.0	[0..12]	[276..5]
gi\|109110260 - gi\|109110260\|ref\|XP_001083368.1\| PREDICTED: proteasome beta 7 subunit [Macaca mulatta]	239.0	[0..16]	[276..9]
gi\|62898273, gi\|... - gi\|62898273\|dbj\|BAD97076.1\| proteasome beta 7 subunit proprotein variant [Homo sapiens], gi\|62897575... gi\|114626634 - gi\|114626634\|ref\|XP_520247.2\| PREDICTED: proteasome beta 7 subunit isoform 5 [Pan troglodytes]	238.0	[0..16]	[276..9]
PSMB7 - proteasome (prosome, macropain) subunit, beta type, 7 gi\|208967176 - gi\|208967176\|dbj\|BAG73602.1\| proteasome (prosome, macropain) subunit, beta type, 7 [synthetic constr...	236.0	[0..16]	[276..9]
gi\|5833465 - gi\|5833465\|gb\|AAD53521.1\|AF155581_1 proteasome subunit beta 7 [Danio rerio]	236.0	[0..19]	[276..10]

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Predicted Domain #1

Region A:
Residues: [1-277]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATADVKSTV PHMDMDRGGA FDFSNCIRNQ AMCKMGGKAP KLTSTGTTIV AVAFKGGLVM  60
   61 GADSRATAGN IIADKHCEKV HKLTESIYAC GAGTAADLDQ VTKMLSGNLR LLELNTGRKA 120
  121 RVITALRQAK QHLFNYQGYI GAYLLIGGVD PTGPHLYMCS ANGTTMAFPF TAQGSGSYAA 180
  181 ITILERDFKV DMTKDEAEKL VQRALEAGMH GDNASGNSLN LVIIEPSETV FKGPIVPEFC 240
  241 KRPEPNDLVY KFQAGATKVL KHKTYKYDVV ESMDITH

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	57.69897
Match:	1iruI
Description:	Proteasome beta subunit (catalytic)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
endopeptidase activity	6.91642761177919	bayes_pls_golite062009
peptidase activity	6.84511694091156	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	6.5973571808298	bayes_pls_golite062009
hydrolase activity	4.47652590304822	bayes_pls_golite062009
threonine-type endopeptidase activity	2.98214579292788	bayes_pls_golite062009
threonine-type peptidase activity	2.98214579292788	bayes_pls_golite062009
catalytic activity	1.19663085909195	bayes_pls_golite062009
binding	0.982918122186083	bayes_pls_golite062009
nucleic acid binding	0.448212653390607	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: