| Protein: | nhr-60 |
| Organism: | Caenorhabditis elegans |
| Length: | 443 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nhr-60.
| Description | E-value | Query Range |
Subject Range |
|
|
280.0 | [0..2] | [438..8] |
|
Region A: Residues: [1-173] |
1 11 21 31 41 51
| | | | | |
1 MIQSSSSISQ DSLDLPSILS TFSADEPEDE PSPTAVKSTK PQRPTECLIC GNSANGHHYD 60
61 VASCNGCKTF FRRMCVSDRS FECKAKGDCF DLTKRKVPLK CRACRHQKCI SVGMNPLAME 120
121 VDEKAASSSN FKKLVKRAQD LEPDDDCQVT AVVNKMQIVK PVDSIESKMQ NIT
|
| Detection Method: |  |
| Confidence: | 21.69897 |
| Match: | 2a66A |
| Description: | Human Liver Receptor Homologue DNA-Binding Domain (hLRH-1 DBD) in Complex with dsDNA from the hCYP7A1 Promoter |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [174-443] |
1 11 21 31 41 51
| | | | | |
1 DMLVYLETKV ERFRKSAYNP HWNEFSGLEY LLESECRIGF GDRFGPMPGW PLRRDQLGPP 60
61 RLPKPPSPGK PRDSQHSQNI KQWFFYNLLT TVEYAKTFMF FHRLSSRDKL ILTRHVALAC 120
121 TNLHISYSSI RRNLEVIIEP DGSEPMTFND THYSASVMSV APLIRCQIKN IEYLLLKAIV 180
181 LCNPAVPDLS AKSQEIISLE RVKYADALFN YCLRSRSDGP PHFAQLIQII DVLERQQRMQ 240
241 KDLHLLLVAP KVAKLPKDLV MRVIEDIMDS
|
| Detection Method: | |
| Confidence: | 46.0 |
| Match: | 1lbdA |
| Description: | LIGAND-BINDING DOMAIN OF THE HUMAN NUCLEAR RECEPTOR RXR-ALPHA |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 5.53061626347066 | bayes_pls_golite062009 |
| DNA binding | 4.92165988569962 | bayes_pls_golite062009 |
| nucleic acid binding | 4.78024150262074 | bayes_pls_golite062009 |
| transcription activator activity | 4.53302455129434 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 4.11614358606713 | bayes_pls_golite062009 |
| transcription factor activity | 4.0914094580319 | bayes_pls_golite062009 |
| ligand-dependent nuclear receptor activity | 3.89763470197726 | bayes_pls_golite062009 |
| binding | 3.85318710398432 | bayes_pls_golite062009 |
| protein binding | 3.21524787168952 | bayes_pls_golite062009 |
| transcription factor binding | 2.68044489404568 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.38308182853979 | bayes_pls_golite062009 |
| steroid hormone receptor activity | 2.30195937604451 | bayes_pls_golite062009 |
| transcription repressor activity | 2.20686235000733 | bayes_pls_golite062009 |
| receptor activity | 2.07573173722434 | bayes_pls_golite062009 |
| transcription cofactor activity | 1.73827483890179 | bayes_pls_golite062009 |
| transcription activator binding | 1.69311899839185 | bayes_pls_golite062009 |
| nuclear hormone receptor binding | 1.60419100774741 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.34794228300778 | bayes_pls_golite062009 |
| retinoic acid receptor binding | 1.28118886948947 | bayes_pls_golite062009 |
| transcription coactivator activity | 1.23834725221597 | bayes_pls_golite062009 |
| molecular transducer activity | 1.19872119297817 | bayes_pls_golite062009 |
| signal transducer activity | 1.19872119297817 | bayes_pls_golite062009 |
| palmitoyl-CoA hydrolase activity | 1.13206308146742 | bayes_pls_golite062009 |
| retinoid X receptor binding | 0.99801784942981 | bayes_pls_golite062009 |
| retinoic acid receptor activity | 0.853869057774515 | bayes_pls_golite062009 |
| protein dimerization activity | 0.797229273848179 | bayes_pls_golite062009 |
| hormone receptor binding | 0.74373733735458 | bayes_pls_golite062009 |
| promoter binding | 0.58091332905515 | bayes_pls_golite062009 |
| protein N-terminus binding | 0.57701453824007 | bayes_pls_golite062009 |
| thyroid hormone receptor activity | 0.49784404390361 | bayes_pls_golite062009 |
| lipid binding | 0.487234838559299 | bayes_pls_golite062009 |
| protein heterodimerization activity | 0.45265806678057 | bayes_pls_golite062009 |
| receptor binding | 0.418843034756825 | bayes_pls_golite062009 |
| ligand-regulated transcription factor activity | 0.202197503742221 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity, enhancer binding | 0.15737167800277 | bayes_pls_golite062009 |
| catalytic activity | 0.106902059021677 | bayes_pls_golite062009 |
