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View Structure Prediction Details

Protein: CE14680
Organism: Caenorhabditis elegans
Length: 335 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE14680.

Description E-value Query
Range
Subject
Range
cpr-5 - thiol protease status:Confirmed UniProt:P43509 protein_id:AAB65346.1
317.0 [0..1] [335..1]

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Predicted Domain #1
Region A:
Residues: [1-335]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLKLLPSLLF ILAASAVVLP RNKLFINHIN SAQKLWTAEH YTTPFEVKNL MKVEHVAAHL  60
   61 DKDIKLAETA DSIPDSYDVR DHWPQCISVN NIRDQSHCGS CWAVAAAEAI SDRTCIASNG 120
  121 DVNTLLSAED ILTCCTGKFN CGDGCEGGYP IQAWRYWVKN GLVTGGSFES QYGCKPYSIA 180
  181 PCGETIDGVT WPECPMKISD TPKCEHHCTG NNSYPIPYDQ DKHFGASAYA IGRSAKQIQT 240
  241 EILAHGPVEV GFIVYEDFYL YKTGIYTHVA GGELGGHAVK MLGWGVDNGT PYWLAANSWN 300
  301 TVWGEKGYFR ILRGVDECGI ESAAVAGMPD LNRRN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 77.39794
Match: 1pbhA
Description: CRYSTAL STRUCTURE OF HUMAN RECOMBINANT PROCATHEPSIN B AT 3.2 ANGSTROM RESOLUTION
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 4.90619850296986 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 4.64381885397949 bayes_pls_golite062009
endopeptidase activity 3.75054525912786 bayes_pls_golite062009
hydrolase activity 3.74079711298952 bayes_pls_golite062009
cysteine-type peptidase activity 2.71117522993364 bayes_pls_golite062009
cysteine-type endopeptidase activity 1.95802900199539 bayes_pls_golite062009
binding 1.49113376575534 bayes_pls_golite062009
cytoskeletal protein binding 1.12653729823589 bayes_pls_golite062009
catalytic activity 1.05972260874031 bayes_pls_golite062009
protein binding 0.874003454509364 bayes_pls_golite062009
tubulin binding 0.80007793113729 bayes_pls_golite062009
microtubule binding 0.752289145309061 bayes_pls_golite062009
small conjugating protein-specific protease activity 0.649171767629235 bayes_pls_golite062009
thiolester hydrolase activity 0.59115205419466 bayes_pls_golite062009
kininogen binding 0.41283715939055 bayes_pls_golite062009
signal transducer activity 0.26868506520228 bayes_pls_golite062009
molecular transducer activity 0.26868506520228 bayes_pls_golite062009
structural molecule activity 0.102555314244558 bayes_pls_golite062009
ubiquitin-specific protease activity 0.0101379718864654 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle