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View Structure Prediction Details

Protein: dnj-22
Organism: Caenorhabditis elegans
Length: 296 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for dnj-22.

Description E-value Query
Range		 Subject
Range
DNAJ_CHRSD - Chaperone protein DnaJ OS=Chromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB 13768)...
 251.0 [0..4] [281..1]
gi|110739057, gi... - gi|30699483|ref|NP_849911.1| DNAJ heat shock protein, putative [Arabidopsis thaliana], gi|30699481|r...
 250.0 [0..8] [291..75]
gi|22298332, gi|... - gi|22298332|ref|NP_681579.1| heat shock protein [Thermosynechococcus elongatus BP-1], gi|22294511|db...
 247.0 [0..3] [281..1]
DNAJ_PSEPK - Chaperone protein DnaJ OS=Pseudomonas putida (strain KT2440) GN=dnaJ PE=3 SV=1
tr|E4R635|E4R635... - Chaperone protein DnaJ OS=Pseudomonas putida (strain BIRD-1) GN=dnaJ PE=3 SV=1
 246.0 [0..4] [289..1]
gi|53612269, gi|... - gi|67158732|ref|ZP_00419593.1| DnaJ central domain (CXXCXGXG):Heat shock protein DnaJ, N-terminal:Ch...
DNAJ_AZOVD - Chaperone protein DnaJ OS=Azotobacter vinelandii (strain DJ / ATCC BAA-1303) GN=dnaJ PE=3 SV=1
 246.0 [0..4] [288..1]
DNAJ2_AROAE - Chaperone protein DnaJ 2 OS=Aromatoleum aromaticum (strain EbN1) GN=dnaJ2 PE=3 SV=1
 245.0 [0..4] [291..1]
DNAJ_SYNEL - Chaperone protein dnaJ OS=Synechococcus elongatus GN=dnaJ PE=3 SV=2
DNAJ_THEEB - Chaperone protein DnaJ OS=Thermosynechococcus elongatus (strain BP-1) GN=dnaJ PE=3 SV=2
 245.0 [0..5] [281..1]
tr|I7C0C3|I7C0C3... - Chaperone protein DnaJ OS=Pseudomonas putida (strain DOT-T1E) GN=dnaJ PE=3 SV=1
DNAJ_PSEP1 - Chaperone protein DnaJ OS=Pseudomonas putida (strain F1 / ATCC 700007) GN=dnaJ PE=3 SV=1
 244.0 [0..4] [289..1]
DNAJ_BURCE - Chaperone protein dnaJ - Burkholderia cepacia (Pseudomonas cepacia)
DNAJ_BURML - (Q5NSW9) Chaperone protein dnaJ
DNAJ_BURM1 - Chaperone protein DnaJ OS=Burkholderia multivorans (strain ATCC 17616 / 249) GN=dnaJ PE=3 SV=1
 244.0 [0..4] [285..1]

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Predicted Domain #1
Region A:
Residues: [1-118] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPLKPGANPY KILHLEKGCT DKEIQKAYRA QCLKWHPDKN LDNKEEAERR FIEAKEAFDF  60
   61 LYDKEKREEY DNREERIRMA QEHHSKRMAE ADGKRKKLIE DLEKREKEFS NGGKRSAD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 24.69897
Match: 1bq0A
Description: J-DOMAIN (RESIDUES 1-77) OF THE ESCHERICHIA COLI N-TERMINAL FRAGMENT (RESIDUES 1-104) OF THE MOLECULAR CHAPERONE DNAJ, NMR, 20 STRUCTURES
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.43290712732733 bayes_pls_golite062009
protein binding 1.5095461875158 bayes_pls_golite062009
transcription regulator activity 1.2131700498174 bayes_pls_golite062009
nucleic acid binding 0.936798066013332 bayes_pls_golite062009
DNA binding 0.8788643398536 bayes_pls_golite062009
catalytic activity 0.106988907594358 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [119-296] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSTPMTAAQQ AKKKKTDQRN FKEEIEAIRR QLEKEVNEEV KQKATLMKTE REKHQKSQEK  60
   61 LTPRLLLKWK TSEGLDYSED DIRKLFSTFG IISHISSAIE KKDRRKRILE FESGANAWGA 120
  121 ELETGNAPMP EITCEWLQPP VETVKKASDE PVKSTNTGAN NLEHMSLDDL EAQIMGGF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.221849
Match: 1nltA
Description: The crystal structure of Hsp40 Ydj1
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle