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Protein Overview: dnj-22

General Information:
Name(s) found: dnj-22 / CE14038 [WormBase]
Description(s) found:
Found 18 descriptions.
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  • WBGene00001040 locus:dnj-22 status:Confirmed UniProt:O17002 protein_id:CCD72919.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 296 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: response to heat [IEALink to PubMed article]
    locomotory behavior [IMPLink to PubMed articleLink to PubMed article]
    nematode larval development [IMPLink to PubMed articleLink to PubMed article]
    morphogenesis of an epithelium [IMPLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed article]
    gamete generation [IMPLink to PubMed articleLink to PubMed article]
    protein folding [IEALink to PubMed article]
    positive regulation of embryonic development [IMPLink to PubMed article]
    growth [IMPLink to PubMed articleLink to PubMed article]
    Molecular Function: heat shock protein binding [IEALink to PubMed article]
    ATP binding [IEALink to PubMed article]
    unfolded protein binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPLKPGANPY KILHLEKGCT DKEIQKAYRA QCLKWHPDKN LDNKEEAERR FIEAKEAFDF  60
   61 LYDKEKREEY DNREERIRMA QEHHSKRMAE ADGKRKKLIE DLEKREKEFS NGGKRSADGS 120
  121 TPMTAAQQAK KKKTDQRNFK EEIEAIRRQL EKEVNEEVKQ KATLMKTERE KHQKSQEKLT 180
  181 PRLLLKWKTS EGLDYSEDDI RKLFSTFGII SHISSAIEKK DRRKRILEFE SGANAWGAEL 240
  241 ETGNAPMPEI TCEWLQPPVE TVKKASDEPV KSTNTGANNL EHMSLDDLEA QIMGGF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..118] PSI-BLAST 24.69897 J-DOMAIN (RESIDUES 1-77) OF THE ESCHERICHIA COLI N-TERMINAL FRAGMENT (RESIDUES 1-104) OF THE MOLECULAR CHAPERONE DNAJ, NMR, 20 STRUCTURES
    2 View Details [119..296] PSI-BLAST 21.221849 The crystal structure of Hsp40 Ydj1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.43290712732733 bayes_pls_golite062009
  • protein binding
    		•  1.5095461875158 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.2131700498174 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.936798066013332 bayes_pls_golite062009
  • DNA binding
    		•  0.8788643398536 bayes_pls_golite062009
  • catalytic activity
    		•  0.106988907594358 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle