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View Structure Prediction Details

Protein: ile-1
Organism: Caenorhabditis elegans
Length: 492 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ile-1.

Description E-value Query
Range
Subject
Range
gi|449432 - gi|449432|prf||1919261A protein ERGIC-53
315.0 [0..22] [492..40]

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Predicted Domain #1
Region A:
Residues: [1-196]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSSRVLLVL LAVIVTIQAQ NTPVFKKFEY KHSFRAPNLA QRDGSIPFWI VSGDAIASGE  60
   61 QLRLAPSMRS RKGIAWNKRA FLESENFQVD IALKIGGQGR VGADGLGIWY TSQLGALGPV 120
  121 FGGNDFWTGM GLFLDSFDND GQKNNPQVSL MLNDGTRSYD HHTDGSQQIL SSCQRDFRNK 180
  181 PYPVRIRIEY LKNVLT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 53.0
Match: 1r1zA
Description: The Crystal structure of the Carbohydrate recognition domain of the glycoprotein sorting receptor p58/ERGIC-53 reveals a novel metal binding site and conformational changes associated with calcium ion binding
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.77315480906007 bayes_pls_golite062009
sugar binding 1.53959484116223 bayes_pls_golite062009
carbohydrate binding 1.40439904952516 bayes_pls_golite062009
transporter activity 1.29150662073327 bayes_pls_golite062009
transmembrane transporter activity 1.07075219961504 bayes_pls_golite062009
substrate-specific transporter activity 0.801327928563072 bayes_pls_golite062009
protein binding 0.657665757061848 bayes_pls_golite062009
signal transducer activity 0.631926547812897 bayes_pls_golite062009
molecular transducer activity 0.631926547812897 bayes_pls_golite062009
monosaccharide binding 0.5678336426881 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.546870122670733 bayes_pls_golite062009
unfolded protein binding 0.534220865159691 bayes_pls_golite062009
receptor activity 0.23954333371021 bayes_pls_golite062009
transmembrane receptor activity 0.00800219256384116 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [197-492]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VHIDDGMQPT PRYELCMRAE NIFLPRNGYF GVSAATGGLA DDHDVLDFSV FSLFNEQQKP  60
   61 VPVAEQIPQQ EKQKYDEEFE RQMKEYEQER AKFKEQHPDK VKEDDEYDPN KYYEDATARE 120
  121 LRLIYESQNA IHQVMQNMDQ RLAQIQQAQT SGVAAAVPHS GGAAPAPVAA GGSFQQHEKN 180
  181 EVITSLRDLT QTIRDMKQYV NEIFTKTYNI DQKIAQGGAG AGGVDSSMHQ KVDSLLNELR 240
  241 TVRATQIQTS GPGAAANCPN ISCVSSTIFM LIIFIQSAII VAVVFVRSKQ DKAKFY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.69897
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle