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View Structure Prediction Details

Protein: CE11480
Organism: Caenorhabditis elegans
Length: 474 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE11480.

Description E-value Query
Range
Subject
Range
gi|118344558, gi... - gi|55771082|dbj|BAD69801.1| cathepsin D1 [Takifugu rubripes], gi|118344558|ref|NP_001072052.1| cathe...
344.0 [0..89] [471..1]

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Predicted Domain #1
Region A:
Residues: [1-88]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKQGFLIYYS RLLLDFRAFF CRALALAIFF VQFSICITQL VQKLFICVNT TFLCAERGEM  60
   61 ITGGTKILRN TFQSIKLEDN RKIFIFHK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [89-474]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFGKLISLLG LVALCSAGQF SISVEKSGSL REQLIREGRY GQELARIQQL STGNVSFFDH  60
   61 FDEYYTAGVR IGTPAQHFQV AFDTTSSNLW VFGVECRSQN CHGGRGRRDR EYNRTASSTF 120
  121 VAGTSSFNLP YDGGHVSGNV GKDTAQFAGF TIQSQDFGIG TAATRLFGET FDGVLGLGWP 180
  181 ATALNGTSTT MQNLLPQLDQ KLFTTYFTKS NMHNGTAGGD IMFGAIDTTH CQSQVNYVPL 240
  241 AYNSFWSYSV DGFSIGTYSR TQTETTIPDT SSGWTGVPNV VLAGIVKATG ATYDWNHQAY 300
  301 TLPCSSTATL PDMVFTIGGN SYNVRAVEYV VNLNLPNGQC ALSLFGTAAS QSGPAWILGD 360
  361 NFLRSYCHVF DFGNSRIGLA KAIQNY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 85.221849
Match: 2psgA
Description: REFINED STRUCTURE OF PORCINE PEPSINOGEN AT 1.8 ANGSTROMS RESOLUTION
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
aspartic-type endopeptidase activity 7.9145950161796 bayes_pls_golite062009
aspartic-type peptidase activity 7.9145950161796 bayes_pls_golite062009
peptidase activity 5.78181196721293 bayes_pls_golite062009
endopeptidase activity 5.4888481808613 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 5.39972232367526 bayes_pls_golite062009
hydrolase activity 4.34796304893506 bayes_pls_golite062009
catalytic activity 1.54514410489082 bayes_pls_golite062009
protein binding 1.24436201877985 bayes_pls_golite062009
binding 1.10054369202721 bayes_pls_golite062009
receptor binding 1.06854757360057 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle