YRC Public Data Repository - Protein Structure Prediction

Protein:	ceh-37
Organism:	Caenorhabditis elegans
Length:	278 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ceh-37.

Description	E-value	Query Range	Subject Range
LHX1_DANRE - LIM/homeobox protein Lhx1 OS=Danio rerio GN=lhx1a PE=2 SV=1	126.0	[0..3]	[271..141]
gi\|109075374, gi... - gi\|109075374\|ref\|XP_001091045.1\| PREDICTED: similar to paired-like homeodomain transcription factor ...	121.0	[0..31]	[272..75]
PITX2 - paired-like homeodomain 2 gi\|114595674, gi... - gi\|114595676\|ref\|XP_001141320.1\| PREDICTED: paired-like homeodomain transcription factor 2 isoform 4...	121.0	[0..10]	[272..54]
gi\|47224946 - gi\|47224946\|emb\|CAG06516.1\| unnamed protein product [Tetraodon nigroviridis]	120.0	[0..3]	[271..141]
gi\|76619484 - gi\|76619484\|ref\|XP_870617.1\| PREDICTED: similar to ALL1 responsive protein ARP1c isoform 2 [Bos taur...	120.0	[0..10]	[272..54]
PITX2_MOUSE - Pituitary homeobox 2 OS=Mus musculus GN=Pitx2 PE=1 SV=2	120.0	[0..2]	[272..46]
gi\|74002160 - gi\|74002160\|ref\|XP_863661.1\| PREDICTED: similar to paired-like homeodomain transcription factor 2 is...	120.0	[0..10]	[272..54]
gi\|149025926, gi... - gi\|9506975\|ref\|NP_062207.1\| paired-like homeodomain transcription factor 2 isoform 2 [Rattus norvegi... gi\|1724116, gi\|1... - gi\|3078013\|gb\|AAC40086.1\| ALL1 responsive protein ARP1a [Mus musculus], gi\|1724116\|gb\|AAB38505.1\| or... gi\|109075378 - gi\|109075378\|ref\|XP_001091165.1\| PREDICTED: similar to paired-like homeodomain transcription factor ...	119.0	[0..31]	[272..29]

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Predicted Domain #1

Region A:
Residues: [1-104]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSYSYFTIP STATTGFNYP VQPMTMFSGA PYNAAMIPRK NRRERTTYSR QQLEILETLF  60
   61 NETQYPDVFA RERVADQIRL QESRIQVWFK NRRAKYRLQE KQKP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	21.0
Match:	1fjlA
Description:	Paired protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	3.57523737355937	bayes_pls_golite062009
DNA binding	3.00143272905695	bayes_pls_golite062009
nucleic acid binding	2.89825020286436	bayes_pls_golite062009
transcription factor activity	2.53664874743748	bayes_pls_golite062009
binding	1.68817361068715	bayes_pls_golite062009
RNA polymerase II transcription factor activity	1.14821760889085	bayes_pls_golite062009
sequence-specific DNA binding	0.46503550280898	bayes_pls_golite062009
transcription repressor activity	0.20862059645422	bayes_pls_golite062009
protein binding	0.111941607625758	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [105-278]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KRSNEKSQEH KSEDQQQTDV LDGEPLKGGS PGYQPQIKSE LESCDGAVAS GKLGTPKSIS  60
   61 PVETTASTTS SNTSAAELQW NGDHKILGFG KNETTTSAAV SPTADNASTP SSSSSITATS 120
  121 SLPTTSSSLS VYNYPAIYPQ WGLDYSTYAN PQYAQFSHNP YAGTPFWYSN GNNL

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: