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View Structure Prediction Details

Protein: acs-6
Organism: Caenorhabditis elegans
Length: 565 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for acs-6.

Description E-value Query
Range
Subject
Range
gi|77996178, gi|... - gi|78044063|ref|YP_360551.1| long-chain-fatty-acid--CoA ligase [Carboxydothermus hydrogenoformans Z-...
526.0 [0..4] [545..12]

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Predicted Domain #1
Region A:
Residues: [1-565]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVFVSKAASV KLSTTTVHER IFEACRIHAS ANKDAVCFID AETTTKKKLY KDVEPTVNSL  60
   61 ATALVKLGFK PGDVASQAFP NCPEFLVAML AVMKCGGAMS NASAIFTDYE LQLQFCDSNT 120
  121 SIVFTDEDRL ARIRRATAKC PGVRKIICLR TFPLRTEFPE NVLDYVELTQ TPDQPINVNV 180
  181 SMDSIALLPY SSGTTGRPKG CQLTHRNIGA MLDVAKAHLE TDVAPAMFGK EKATWHKEHT 240
  241 VLLLPWYHAY GLNTMFETIL LGMTGIVFKK FDTIVMLNRI KFYKVKLAWL VPPMLIFLAK 300
  301 DPMVPIFNTA PFLKVIMSAG ATAGKQLCEE VSKRFPNAWL CQAYGMTEMV QFTTIPRFED 360
  361 GNCFETVGNL ASTYELKILD KEKKEITTIN TVGQLCFRGP TVMKGYLKRE EADIIDKDGF 420
  421 LLTGDLGSID DKGRIHVTGR IKELIKVNGM QVPPVEIEDV LLLHPKVKDC AVIGVPDEHK 480
  481 GESPKAYIVK KDHTLTEAEL TEFVRQKLSS YKWIDTYEFI DSIPKLPSGK IQRKKLKKMA 540
  541 ESSGSTESEA SEPSQSERSS HSIRR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 109.0
Match: 1ba3A
Description: FIREFLY LUCIFERASE IN COMPLEX WITH BROMOFORM
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ligase activity, forming carbon-sulfur bonds 5.10123876514454 bayes_pls_golite062009
fatty acid ligase activity 4.83067429373059 bayes_pls_golite062009
long-chain fatty acid-CoA ligase activity 4.72692389032116 bayes_pls_golite062009
acetate-CoA ligase activity 4.48129067128523 bayes_pls_golite062009
acid-thiol ligase activity 4.28278725989432 bayes_pls_golite062009
CoA-ligase activity 4.12850865352867 bayes_pls_golite062009
Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity 2.74744781333102 bayes_pls_golite062009
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) 2.74744781333102 bayes_pls_golite062009
luciferin monooxygenase activity 2.67396462766343 bayes_pls_golite062009
ligase activity 2.49556073715112 bayes_pls_golite062009
transcription regulator activity 2.31193176808353 bayes_pls_golite062009
catalytic activity 1.83545185797733 bayes_pls_golite062009
binding 1.5312519256537 bayes_pls_golite062009
transcription repressor activity 1.2638869228049 bayes_pls_golite062009
acetoacetate-CoA ligase activity 1.03788694975627 bayes_pls_golite062009
adenyl ribonucleotide binding 0.519946577969422 bayes_pls_golite062009
adenyl nucleotide binding 0.500908589473269 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.398310577427897 bayes_pls_golite062009
purine ribonucleotide binding 0.283236127656661 bayes_pls_golite062009
ribonucleotide binding 0.283214450918389 bayes_pls_golite062009
purine nucleotide binding 0.271435169336222 bayes_pls_golite062009
nucleotide binding 0.263031065274377 bayes_pls_golite062009

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