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View Structure Prediction Details

Protein: CE06215
Organism: Caenorhabditis elegans
Length: 347 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE06215.

Description E-value Query
Range
Subject
Range
gi|238715026, gi... - gi|77958654|ref|ZP_00822684.1| COG1062: Zn-dependent alcohol dehydrogenases, class III [Yersinia ber...
336.0 [0..3] [346..4]

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Predicted Domain #1
Region A:
Residues: [1-347]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQDNLSAVL YGVDDLRLEQ VPIPKPGPNQ VLVKVHTVGI CGSDVHYWTH GAIGPFVVKE  60
   61 PMIVGHETSG IVSEVGNEVK HLKVGDRIAM EPGLPCKLCE HCKTGRYNLC PEMRFFATPP 120
  121 VHGTLSRFVV HDADFCFKLP DNLSFEDGAL IEPLSVAIHA CRRGNVQMGH RVLVLGAGPI 180
  181 GVLNLITAKA VGAGKVVITD LDDGRLALAK KLGADATINV KGKSLDAVKS EIITALGDQQ 240
  241 PDVCIECTGA QPSIETAITT TKSGGVIVLV GLGADRVEIP IIESATREVD MRGIFRYVNC 300
  301 YPTAIELISS GKLNLSGLTR AHYKLEETQE AFKRTQKADV IKVFIQC

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 88.39794
Match: 1pl6A
Description: Human SDH/NADH/inhibitor complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ethanol binding 4.47659026306883 bayes_pls_golite062009
NAD or NADH binding 4.35058438816264 bayes_pls_golite062009
retinol dehydrogenase activity 4.1750549780559 bayes_pls_golite062009
oxidoreductase activity 3.09625241707629 bayes_pls_golite062009
L-iditol 2-dehydrogenase activity 3.00103406168296 bayes_pls_golite062009
alcohol binding 2.97042200128883 bayes_pls_golite062009
alcohol dehydrogenase (NAD) activity 2.94416173750168 bayes_pls_golite062009
retinol binding 2.89007863838685 bayes_pls_golite062009
all-trans retinal binding 2.84803957533249 bayes_pls_golite062009
chaperone binding 2.79912653573494 bayes_pls_golite062009
S-(hydroxymethyl)glutathione dehydrogenase activity 2.58673703881996 bayes_pls_golite062009
hydroxymethylfurfural reductase (NADH) activity 2.2999175117758 bayes_pls_golite062009
hydroxymethylfurfural reductase activity 2.2999175117758 bayes_pls_golite062009
alcohol dehydrogenase activity, zinc-dependent 2.26153457113968 bayes_pls_golite062009
NADPH:quinone reductase activity 2.16668841986245 bayes_pls_golite062009
benzaldehyde dehydrogenase activity 2.03039843216597 bayes_pls_golite062009
catalytic activity 1.79741889688267 bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors 1.65338499044318 bayes_pls_golite062009
retinoid binding 1.54383322726845 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1.47309297191111 bayes_pls_golite062009
isoprenoid binding 1.42961392805059 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors 1.38219425408212 bayes_pls_golite062009
3-hydroxyacyl-CoA dehydrogenase activity 1.07006097264025 bayes_pls_golite062009
binding 0.784517759335365 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 0.527946013169731 bayes_pls_golite062009
L-arabinitol 2-dehydrogenase activity 0.382131941157781 bayes_pls_golite062009
hydroxymethylfurfural reductase (NADPH) activity 0.382131941157781 bayes_pls_golite062009
glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity 0.361275519814065 bayes_pls_golite062009
coenzyme binding 0.35922330382799 bayes_pls_golite062009
3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity 0.320177384202291 bayes_pls_golite062009
glyceraldehyde-3-phosphate dehydrogenase activity 0.298691872199351 bayes_pls_golite062009
ATPase activity 0.275256680720412 bayes_pls_golite062009
enoyl-CoA hydratase activity 0.250698007650211 bayes_pls_golite062009
nucleic acid binding 0.179327587154303 bayes_pls_golite062009
methylenetetrahydrofolate dehydrogenase activity 0.169301675015808 bayes_pls_golite062009
methenyltetrahydrofolate cyclohydrolase activity 0.162625185692811 bayes_pls_golite062009
DNA binding 0.0742540086107448 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle