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View Structure Prediction Details

Protein: CE06190
Organism: Caenorhabditis elegans
Length: 417 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE06190.

Description E-value Query
Range
Subject
Range
gi|86826424, gi|... - gi|86826424|gb|AAI12485.1| Lecithin-cholesterol acyltransferase [Bos taurus], gi|76640158|ref|XP_588...
420.0 [0..26] [415..39]

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Predicted Domain #1
Region A:
Residues: [1-112]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRDILVSLCI FLVLIGKSDT KWFGKFGRSQ AKGLPVILVP GDGGSQLESN LTGKPSVVHY  60
   61 VCSKQTADYF DLWLNLQLFT PLVIDCWADN MQLVFNTTTG LSENMPGVDI RV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [113-417]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AGFGATESVE WLDKSKASQG RYFFDIVDSM VSWGYRRGKN VIGAPFDWRK SPNELNDYLI  60
   61 QLKSLIETTY RWNDNQKIVL VGHSMGNPLS LYFLNNYVDQ AWKDKYISSF VSLAAPWAGS 120
  121 MQIVRLFASG YNMNYYRVIL PPSSLRAMQR SFSSSAFLFP SPVAWKPHEI LATTADKNYT 180
  181 VGNIKEFFQD INYMVGWEQY KQAARLNGNL SSPGVPVHCI YGTGVPTPEK FSWAPGYFPD 240
  241 YPPTEFMGDG DGTVNKKSAT VCTNWIGNNN GYKVTVHEVF QADHMAILKH PNAIELVRKA 300
  301 IFQLI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 24.30103
Match: 1ex9A
Description: Lipase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
palmitoyl-(protein) hydrolase activity 4.96081517583876 bayes_pls_golite062009
hydrolase activity 3.20549979663539 bayes_pls_golite062009
phospholipase A1 activity 2.92902750888377 bayes_pls_golite062009
carboxylesterase activity 2.10340684157921 bayes_pls_golite062009
phospholipase activity 1.98964694567462 bayes_pls_golite062009
lipase activity 1.95656432876646 bayes_pls_golite062009
palmitoyl-CoA hydrolase activity 1.62335985481548 bayes_pls_golite062009
catalytic activity 1.39629727416851 bayes_pls_golite062009
sterol esterase activity 1.21262745914703 bayes_pls_golite062009
thiolester hydrolase activity 1.18565704009692 bayes_pls_golite062009
peptidase activity 0.946698616106528 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 0.786172015267385 bayes_pls_golite062009
triglyceride binding 0.758096468396509 bayes_pls_golite062009
serine hydrolase activity 0.527527404338 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.39970089568167 bayes_pls_golite062009
acyl-CoA thioesterase activity 0.35429970866093 bayes_pls_golite062009
binding 0.351031277062254 bayes_pls_golite062009
acylglycerol lipase activity 0.345658974420231 bayes_pls_golite062009
serine-type peptidase activity 0.33062249657108 bayes_pls_golite062009
lipoprotein binding 0.183648119837274 bayes_pls_golite062009
triglyceride lipase activity 0.05324087110088 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle