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View Structure Prediction Details

Protein: tag-173
Organism: Caenorhabditis elegans
Length: 366 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for tag-173.

Description E-value Query
Range		 Subject
Range
gi|91076836 - gi|91076836|ref|XP_974707.1| PREDICTED: similar to AGAP007531-PA [Tribolium castaneum]
 348.0 [0..21] [366..27]

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Predicted Domain #1
Region A:
Residues: [1-366] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSRAVSLFS KCGSRISQTR GKAHFTFQPS TTLPAGLENL EKTKMNLMQS VNEAMRIAME  60
   61 TDDSAVLFGE DVAFGGVFRC SLDLQKKFGK DRVFNTPLCE QGIAGFGIGV AAAGATAIAE 120
  121 IQFGDYIFPA YDQLVNEAAK FRYRSGNQFD CGKLTVRTTW GAVGHGALYH SQSPEANFTH 180
  181 TPGLKLVVPR GPVQAKGLLL SCIRDPNPCI FFEPKILYRL ASEDVPTGDY TIPLGQAETV 240
  241 RSGKDLTLVA WGTQVHVALE AAQLAKEKLN ADVEVIDLQT IQPWDEDHVV ESVQKTGRLI 300
  301 VTHEAPISSG FGAEIASTVQ KRCFLNLESP IDRVAGFDTP FPHVHEPFYL PTVHRVFDAI 360
  361 KKSVNY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 92.69897
Match: 1dtwB
Description: Branched-chain alpha-keto acid dehydrogenase, Pyr module; Branched-chain alpha-keto acid dehydrogenase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
pyruvate dehydrogenase activity 11.3856674722026 bayes_pls_golite062009
pyruvate dehydrogenase (acetyl-transferring) activity 11.0549577473177 bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor 10.8180381281695 bayes_pls_golite062009
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity 7.00951713446616 bayes_pls_golite062009
alpha-ketoacid dehydrogenase activity 6.25236550086321 bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors 5.65146926050423 bayes_pls_golite062009
acetolactate synthase activity 4.51986503762195 bayes_pls_golite062009
cyclin-dependent protein kinase 5 activator regulator activity 3.00128844859152 bayes_pls_golite062009
2-oxoisovalerate dehydrogenase (acylating) activity 3.00128844859152 bayes_pls_golite062009
transferase activity, transferring aldehyde or ketonic groups 1.29819462996182 bayes_pls_golite062009
transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer 0.667418924427388 bayes_pls_golite062009
binding 0.551586872853971 bayes_pls_golite062009
catalytic activity 0.545407789079971 bayes_pls_golite062009
oxidoreductase activity 0.281475773435032 bayes_pls_golite062009
pyruvate decarboxylase activity 0.198062360371269 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle