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View Structure Prediction Details

Protein: ceh-43
Organism: Caenorhabditis elegans
Length: 273 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ceh-43.

Description E-value Query
Range
Subject
Range
gi|47222353 - gi|47222353|emb|CAG05102.1| unnamed protein product [Tetraodon nigroviridis]
135.0 [0..4] [214..59]
gi|109470122 - gi|109470122|ref|XP_001063903.1| PREDICTED: similar to Homeobox protein Hox-D8 (Hox-4.3) (Hox-5.4) [...
133.0 [0..30] [174..123]
gi|27374237 - gi|27374237|gb|AAO00997.1| Antp-PA [Drosophila erecta]
gi|27374285 - gi|27374285|gb|AAO01039.1| Antp-PA [Drosophila pseudoobscura]
131.0 [0..101] [182..1]
gi|148666244, gi... - gi|22477523|gb|AAH36986.1| Hoxa7 protein [Mus musculus], gi|148666244|gb|EDK98660.1| homeobox A7, is...
131.0 [0..96] [180..2]
gi|5441871 - gi|5441871|dbj|BAA82371.1| Hoxb-5 [Paralichthys olivaceus]
130.0 [0..96] [177..5]
HXB5_CHICK - Homeobox protein Hox-B5 (Fragment) OS=Gallus gallus GN=HOXB5 PE=3 SV=1
130.0 [0..96] [177..1]
gi|86560752 - gi|86560752|gb|ABD04657.1| Hox7 homeobox protein [Nereis virens]
gi|86560752|gb|A... - Hox7 homeobox protein [Nereis virens]
130.0 [0..100] [187..1]
gi|745777, gi|52... - gi|745777|prf||2016458D Hox-5 gene, gi|520614|emb|CAA84517.1| Hox-5 homeodomain protein [Branchiosto...
129.0 [0..98] [179..2]

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Predicted Domain #1
Region A:
Residues: [1-167]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDPSKGFEYV AGDYYQTSGV APPTSNGAGS NVSPYFPYHA YPTSSTNGAT GGSMYGTPQQ  60
   61 TSAYAMYPPG PGSSPEEAFP EHTTTKIVEG CEAKYNVKGK KMRKPRTIYN SSQLQMLQKK 120
  121 FQKTQYLALP DRAALAHELG LSQTQVKIWF QNRRSKQKKQ KGGSSDH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.0
Match: 1b72A
Description: Homeobox protein hox-b1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.13863038737912 bayes_pls_golite062009
DNA binding 4.66369707598026 bayes_pls_golite062009
nucleic acid binding 4.20953772435302 bayes_pls_golite062009
transcription factor activity 4.06706589695599 bayes_pls_golite062009
binding 3.02779747447702 bayes_pls_golite062009
sequence-specific DNA binding 2.41271657675151 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.26183812259792 bayes_pls_golite062009
transcription repressor activity 1.91962622287073 bayes_pls_golite062009
transcription activator activity 1.77700860354597 bayes_pls_golite062009
transcription factor binding 1.40653841901929 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.14886080629275 bayes_pls_golite062009
chromatin binding 0.876241359231159 bayes_pls_golite062009
transcription cofactor activity 0.84983974758882 bayes_pls_golite062009
protein binding 0.830419844171551 bayes_pls_golite062009
transcription corepressor activity 0.25931464844298 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [168-273]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASDEEDDDTE ESKPESPPMG ESVMIQESSE PRTLVSSSIK TEMKEEYPPM TLNEQYASPY  60
   61 LYGSDFSTIL PPSQGFPNNA LYNTAGAYPS IDYTNGVYQN TLYKYV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle