| Protein: | brf-1 |
| Organism: | Caenorhabditis elegans |
| Length: | 759 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for brf-1.
| Description | E-value | Query Range |
Subject Range |
|
|
440.0 | [0..3] | [614..4] |
|
Region A: Residues: [1-62] |
1 11 21 31 41 51
| | | | | |
1 MVRTCSNCGS SEIDEDAARG DATCTACGTV LEESIVVTEN QFQERAGGSG HTLVGQFVSS 60
61 ER
|
| Detection Method: |  |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [63-284] |
1 11 21 31 41 51
| | | | | |
1 AAANNFNGMG SQESREMTYA KGRKVIDELG SQLRINSHCM NTAFNFYKMC VSRNLTRGRN 60
61 RSSVVAVCMY ITCRLENTAH LLLDFSDVTQ INVFDLGRNL NYLSRSLRIN LPSTDPCLYI 120
121 MRFACVLDFG DKQKEVVNLA TRLVQRMKRD WMSTGRRPTG ICGAALLIAA RSLNFNRSIN 180
181 DIVRVVHISE GVIRKRLDEF SQTPSGSLTI DEFSTVDLEH SE
|
| Detection Method: | |
| Confidence: | 64.0 |
| Match: | 1c9bA |
| Description: | Transcription factor IIB (TFIIB), core domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| general RNA polymerase II transcription factor activity | 5.81887489496763 | bayes_pls_golite062009 |
| binding | 2.94365164362032 | bayes_pls_golite062009 |
| transcription regulator activity | 2.795846725429 | bayes_pls_golite062009 |
| DNA binding | 1.6980508926231 | bayes_pls_golite062009 |
| nucleic acid binding | 1.63159454080484 | bayes_pls_golite062009 |
| cyclin-dependent protein kinase regulator activity | 1.61958639505157 | bayes_pls_golite062009 |
| protein binding | 1.49399866760259 | bayes_pls_golite062009 |
| protein kinase regulator activity | 1.48643751045614 | bayes_pls_golite062009 |
| kinase regulator activity | 1.34524931958191 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 1.09952334871968 | bayes_pls_golite062009 |
| transcription factor activity | 1.0145450763465 | bayes_pls_golite062009 |
| transcription factor binding | 0.749278791251235 | bayes_pls_golite062009 |
| enzyme regulator activity | 0.502596616605714 | bayes_pls_golite062009 |
| transcription coactivator activity | 0.138191616709499 | bayes_pls_golite062009 |
| transcription activator activity | 0.0696060248241566 | bayes_pls_golite062009 |
|
Region A: Residues: [285-410] |
1 11 21 31 41 51
| | | | | |
1 DPPAYRESRR KAREDQLRKE AEQAESMKEQ LGEMEAHVEA ALDKKRKEKF SKSPYARMIS 60
61 ENLGKENDKM QTLTETVVES SGLEKGADEM VRNEIINTVF NAAEEDPCTS NSLEKYDKYR 120
121 PSLESL
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [411-511] |
1 11 21 31 41 51
| | | | | |
1 GIKRTSEPEP EPVPHPIVNA DLEEDISDSE IDSYILTESE VAIKTDYWMK ANGEAMKEIE 60
61 EKKRERELNG GVKKKKPRSN RKTDTTSTSV ASAVEKVIAE K
|
| Detection Method: | |
| Confidence: | 2.58 |
| Match: | 1ngmB |
| Description: | TBP-binding domain of the transcription factor IIIb Brf1 subunit |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [512-576] |
1 11 21 31 41 51
| | | | | |
1 KLSNKVNYEM LKDLETMATG IKRDIRESTP APVTPISIKV DSSDVTPDTL SKSEKIARGK 60
61 NIRSQ
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [577-759] |
1 11 21 31 41 51
| | | | | |
1 ASESTIQKLR SIFDLTEECS ETSKNSSPKV NLKVESASPS TSEVSSIEHK PFVPPARSRY 60
61 AKVKPIIGAK KLAALNEVKN VHTVPEPSAP AEPIVSEAPL QVKTSSSDPI VTSTEVPSVA 120
121 EPPAPIQNVE EAKPIVPVKS RYAKAKPNLK PIKQKTAVDV VTVGEGESSE PSAKRTKAEH 180
181 LES
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
