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View Structure Prediction Details

Protein: tag-246
Organism: Caenorhabditis elegans
Length: 446 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for tag-246.

Description E-value Query
Range
Subject
Range
gi|50806703 - gi|50806703|ref|XP_424488.1| PREDICTED: similar to SMARCD1 protein [Gallus gallus]
660.0 [0..3] [446..284]

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Predicted Domain #1
Region A:
Residues: [1-68]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQTQARPPVP QGPRFNHPAT PQQVRRPINA PLPGQTAQIQ GNRGPQPPKK KKRYADKLIQ  60
   61 PKVRELVP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [69-218]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESQAYMDLLA FEQKLDSTIT RKKIDVQEAL KRPQKIKKRL RIYISHTFIA GKEPEKEGDD  60
   61 ASVPMWELRV EGRLLDDMQH PTVGANPRPA PKRKFSSFFK SLVIELDKDI YGPDNHLVEW 120
  121 HRTPQTNETD GFQVKRPGDR PVKCTILLLL 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [219-309]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DYQPMKFKLH PRLAKVLGIA AETRPRIIEA LWQYIKTHKL QDPQDRDTIN NDLFLEQCFG  60
   61 VSKMRFMEIP QRLHQLLQQP DPLVLNHIIQ R

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 28.09691
Match: 1uhrA
Description: Solution structure of the SWIB domain of mouse BRG1-associated factor 60a
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.01592136607858 bayes_pls_golite062009
basal transcription repressor activity 3.31155980072144 bayes_pls_golite062009
binding 2.67987108623459 bayes_pls_golite062009
transcription coactivator activity 2.58234407051051 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 2.32480271621458 bayes_pls_golite062009
transcription repressor activity 1.98538788872171 bayes_pls_golite062009
transcription activator activity 1.83085389017135 bayes_pls_golite062009
transcription factor binding 1.73032563380905 bayes_pls_golite062009
transcription cofactor activity 1.60414428986898 bayes_pls_golite062009
protein binding 1.58138506346812 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.06026105710513 bayes_pls_golite062009
structural molecule activity 0.66106995897056 bayes_pls_golite062009
catalytic activity 0.121624777548864 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [310-385]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PDDGQDKTSA CYDIDVELED PVKQQMANFV HNQTNANDIQ LLDQKIFDLV DQINEMKLRR  60
   61 DFFLRFSNEP SGFIKK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [386-446]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WVVSQNSDLK TLTESSGDGE SDRYATTYST TDTDEGVSRY MYQKIQQKRA ELEQSLGIRN  60
   61 N

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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