YRC Public Data Repository - Protein Structure Prediction

Protein:	elg1
Organism:	Schizosaccharomyces pombe
Length:	920 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for elg1.

Description	E-value	Query Range	Subject Range
gi\|70731344, gi\|... - gi\|70731344\|ref\|YP_261085.1\| ATP-dependent protease La [Pseudomonas fluorescens Pf-5], gi\|68345643\|g... gi\|7644385 - gi\|7644385\|gb\|AAF65564.1\|AF250140_1 protease Lon [Pseudomonas fluorescens]	341.0	[0..71]	[873..27]
gi\|48729866, gi\|... - gi\|77459917\|ref\|YP_349424.1\| Lon-A peptidase [Pseudomonas fluorescens Pf0-1], gi\|77383920\|gb\|ABA7543...	339.0	[0..71]	[873..27]
gi\|213926439, gi... - gi\|213968836\|ref\|ZP_03396977.1\| ATP-dependent protease La [Pseudomonas syringae pv. tomato T1], gi\|2... gi\|28854128, gi\|... - gi\|28870879\|ref\|NP_793498.1\| ATP-dependent protease La [Pseudomonas syringae pv. tomato str. DC3000]... tr\|Q87YR8\|Q87YR8... - Lon protease OS=Pseudomonas syringae pv. tomato (strain DC3000) GN=lon-1 PE=3 SV=1	338.0	[0..71]	[873..27]
gi\|62549363 - gi\|62549363\|gb\|AAX87000.1\| ATP-dependent protease [Pseudomonas syringae pv. tabaci]	337.0	[0..71]	[873..27]
gi\|22532108 - gi\|22532108\|gb\|AAM97840.1\|AF447727_2 Lon protease [Pseudomonas syringae]	336.0	[0..71]	[873..27]
gi\|71554964, gi\|... - gi\|71734411\|ref\|YP_273937.1\| ATP-dependent protease La [Pseudomonas syringae pv. phaseolicola 1448A]...	335.0	[0..71]	[873..27]
gi\|63255701, gi\|... - gi\|66044994\|ref\|YP_234835.1\| peptidase S16, ATP-dependent protease La [Pseudomonas syringae pv. syri...	334.0	[0..71]	[873..27]
gi\|28198388, gi\|... - gi\|28198388\|ref\|NP_778702.1\| ATP-dependent serine proteinase La [Xylella fastidiosa Temecula1], gi\|2...	333.0	[0..71]	[892..38]
gi\|11265367 - pir\|\|C82712 ATP-dependent serine proteinase La XF1189 [imported] - Xylella fastidiosa (strain 9a5c) gi\|9106159, gi\|1... - gi\|9106159\|gb\|AAF83999.1\|AE003953_3 ATP-dependent serine proteinase La [Xylella fastidiosa 9a5c], gi...	333.0	[0..71]	[892..56]
gi\|26989026, gi\|... - gi\|26989026\|ref\|NP_744451.1\| ATP-dependent protease La [Pseudomonas putida KT2440], gi\|24983850\|gb\|A...	330.0	[0..71]	[873..27]

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Predicted Domain #1

Region A:
Residues: [1-90]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQIVGYLSAD SQSNPDLKSE NEAKEEKPIG RRHTMSPVPA TSENKYFGKS PLSGSRKPRR  60
   61 SRSLHKERSY MRKFFDMDME ESKDFENDQS

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [91-256]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LLVTLKVSTS LGQKIENILH PKLSNDTNST AFPPAKSSGE ASDTNILVEN INSQETVNSS  60
   61 PLVSELHYSN LADSPSNLRN TVTSMHPFFM SKSVKKNSEI KFVSEERGGT KPERLLDPLW 120
  121 PTPDSQSMLE YAGSIEPSVF WFPKKHLEEA ILEETSHLSF KEVLSS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	63.69897
Match:	1oz4A
Description:	VCP/p97
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [257-619]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TTANMITPLA EKNKTEVLQV TPSKLHTFAL ESLCFSPAPF IQKVLSRLLP SDPNVEMPMI  60
   61 PQILEKGLWV SKYAPSKTQD CCAFSQCLSK IADWLRSCRL TKPESSSVPP SSSISRSSTI 120
  121 HSCTSSKRNE DSLSESDFEP DIIEEEDDSD EFNPSVSRKK AKLTSSQFSN WMLVTGVTGI 180
  181 GKTSCLYAIC RELNFEVVEI HPGMRRSGKE LLERIGELTQ SHIVDKSRLN NTPDILILLE 240
  241 EVDILFQDDR GFWQAVSTLI EKSKRPVVMT CNETDFLPSA FLQEDHIVQF QSISSALLTD 300
  301 YISSVLYADR CIISRNVVES ISYRYGSDLR GILMQLNFWS LVNFPSLPSK DKQDDSHEPF 360
  361 IEA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	6.522879
Match:	2c9oA
Description:	No description for 2c9oA was found.

Predicted Domain #4

Region A:
Residues: [620-728]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TISAFDEGVG VYNPRIQTSE DLLQTYSEEQ MGDIGLLFMP NLVNWRKVCV PKSEMEEKEA  60
   61 IMEKLIYSHQ YADSLSYVDY RFSSQPTIYE TYELMNDSAS FEDMSLECR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	29.045757
Match:	1xxiB
Description:	ADP Bound E. coli Clamp Loader Complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
pyrophosphatase activity	2.23646936731119	bayes_pls_golite062009
binding	1.62860302498201	bayes_pls_golite062009
catalytic activity	1.32370671504792	bayes_pls_golite062009
DNA-dependent ATPase activity	1.2537888487362	bayes_pls_golite062009
protein binding	0.324679002546113	bayes_pls_golite062009
nucleoside-triphosphatase activity	0.248432446853676	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	0.217252531553173	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	0.215962398124297	bayes_pls_golite062009
ATPase activity	0.0740243885501273	bayes_pls_golite062009

Predicted Domain #5

Region A:
Residues: [729-825]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DNCANAFQDN LVGFPTISNP FHANAPPEPH ELKLQYHSFC FINNLFSKSS LKAISSNDSI  60
   61 VPKALNNREL QLSALASTIG YKLDPDDVYN ILSFLSF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	59.0
Match:	2ce7A
Description:	EDTA treated
Matching Structure (courtesy of the PDB):

Predicted Domain #6

Region A:
Residues: [826-920]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ANSQVTSYTP PNSIDRPNDI LILEVAPFVR CMRRYDRIRL NSYKLLLSSK GRSASHISRR  60
   61 GAASILRSAG YNYGRLQYLE GSDRILSTWF STTLD

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: