YRC Public Data Repository - Protein Structure Prediction

Protein:	SPAC227.14
Organism:	Schizosaccharomyces pombe
Length:	235 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC227.14.

Description	E-value	Query Range	Subject Range
gi\|48425793, gi\|... - gi\|48425800\|pdb\|1UJ2\|B Chain B, Crystal Structure Of Human Uridine-Cytidine Kinase 2 Complexed With ...	212.0	[0..9]	[235..4]
UCK2A_DANRE - Uridine-cytidine kinase 2-A OS=Danio rerio GN=uck2a PE=2 SV=1	210.0	[0..9]	[235..2]
gi\|76611769 - gi\|76611769\|ref\|XP_614178.2\| PREDICTED: similar to uridine-cytidine kinase 2 [Bos taurus]	210.0	[0..11]	[235..221]
gi\|42407979, gi\|... - gi\|50947885\|ref\|XP_483470.1\| putative uridine kinase/uracil phosphoribosyltransferase [Oryza sativa ...	210.0	[0..23]	[235..65]
gi\|81244853, gi\|... - gi\|82543442\|ref\|YP_407389.1\| uridine/cytidine kinase [Shigella boydii Sb227], gi\|81244853\|gb\|ABB6556...	209.0	[0..1]	[235..1]
gi\|26350013 - gi\|26350013\|dbj\|BAC38646.1\| unnamed protein product [Mus musculus]	209.0	[0..9]	[235..2]
gi\|237704523, gi... - gi\|237704523\|ref\|ZP_04535004.1\| uridine/cytidine kinase [Escherichia sp. 3_2_53FAA], gi\|226900889\|gb... gi\|81241571, gi\|... - gi\|82777423\|ref\|YP_403772.1\| uridine/cytidine kinase [Shigella dysenteriae Sd197], gi\|81241571\|gb\|AB... gi\|25321570, gi\|... - pir\|\|A64973 uridine kinase (EC 2.7.1.48) - Escherichia coli (strain K-12), gi\|25321570\|pir\|\|D85833 u... gi\|1788380, gi\|1... - gb\|AAC75127.1\| uridine/cytidine kinase [Escherichia coli K12], gi\|16130006\|ref\|NP_416570.1\| uridine... gi\|110615583, gi... - gi\|110806035\|ref\|YP_689555.1\| uridine kinase [Shigella flexneri 5 str. 8401], gi\|110615583\|gb\|ABF042... gi\|13362342, gi\|... - gi\|15832127\|ref\|NP_310900.1\| uridine kinase [Escherichia coli O157:H7], gi\|13362342\|dbj\|BAB36296.1\| ... gi\|12516265, gi\|... - gi\|15802548\|ref\|NP_288574.1\| uridine kinase [Escherichia coli O157:H7 EDL933], gi\|12516265\|gb\|AAG571... gi\|73856068, gi\|... - gi\|74312591\|ref\|YP_311010.1\| uridine/cytidine kinase [Shigella sonnei Ss046], gi\|73856068\|gb\|AAZ8877... gi\|13362342, gi\|... - gi\|15832127\|ref\|NP_310900.1\| uridine kinase [Escherichia coli O157:H7 str. Sakai], gi\|13362342\|dbj\|B...	208.0	[0..1]	[235..1]

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Predicted Domain #1

Region A:
Residues: [1-235]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALQVDAPDV SSYDELYNRA VELLKHQQRV LIGLAGGPGS GKSTLCAILA KAWNERFGSE  60
   61 IVKIIPMDGF HYSLEELDRF DNPEKARALR GAEWTFDADL FYSLVRLMKK ITDRELYAPS 120
  121 FDHAIGDPVV DDICVEPKNR ILIFEGNYLL LNKPPWSDAC KLYDIKAYLP VEHSVARARV 180
  181 AHRHLVSGLC ATEEEAIERT DRNDMINLTF VEKNMVTPDI VLQQLRLKTV KTSSL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	55.154902
Match:	1udwA
Description:	Crystal structure of human uridine-cytidine kinase 2 complexed with a feedback-inhibitor, CTP
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.89648142312455	bayes_pls_golite062009
nucleic acid binding	1.08697924060619	bayes_pls_golite062009
catalytic activity	1.00104173493322	bayes_pls_golite062009
DNA binding	0.702147676354075	bayes_pls_golite062009
hydrolase activity	0.420858111948277	bayes_pls_golite062009
transcription regulator activity	0.287777990975748	bayes_pls_golite062009
nucleobase, nucleoside, nucleotide kinase activity	0.12351419478929	bayes_pls_golite062009
helicase activity	0.0775311459068899	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: