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View Structure Prediction Details

Protein: rsc9
Organism: Schizosaccharomyces pombe
Length: 780 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for rsc9.

Description E-value Query
Range
Subject
Range
gi|39968801, gi|... - gi|39968801|ref|XP_365791.1| hypothetical protein MGG_02493 [Magnaporthe grisea 70-15], gb|EAA54508....
545.0 [0..6] [776..37]
gi|28918624, gi|... - gi|32405196|ref|XP_323211.1| hypothetical protein [Neurospora crassa], gi|28918624|gb|EAA28295.1| hy...
gi|85085616 - gi|85085616|ref|XP_957531.1| hypothetical protein [Neurospora crassa OR74A]
515.0 [0..5] [693..1]
gi|42553441, gi|... - gi|46135959|ref|XP_389671.1| hypothetical protein FG09495.1 [Gibberella zeae PH-1], gi|42553441|gb|E...
512.0 [0..5] [776..1]
gi|88177715, gi|... - gi|88177715|gb|EAQ85183.1| hypothetical protein CHGG_09197 [Chaetomium globosum CBS 148.51], gi|1162...
457.0 [0..18] [693..13]
gi|49088496, gi|... - gi|67522945|ref|XP_659533.1| hypothetical protein AN1929.2 [Aspergillus nidulans FGSC A4], ref|XP_40...
418.0 [0..133] [777..26]
gi|58012117 - gi|58012117|gb|AAU20329.2| ARID2 [Homo sapiens]
405.0 [0..16] [621..9]
gi|220700037, gi... - gi|238487840|ref|XP_002375158.1| chromatin remodeling complex subunit (Rsc9), putative [Aspergillus ...
gi|169769825 - gi|169769825|ref|XP_001819382.1| hypothetical protein [Aspergillus oryzae RIB40]
gi|83767241 - gi|83767241|dbj|BAE57380.1| unnamed protein product [Aspergillus oryzae]
385.0 [0..133] [777..26]

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Predicted Domain #1
Region A:
Residues: [1-136]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQVIQGAVE EPVYSNKSLT NENDSFLSLI ESFSQERGVP IDINPKIGRK PILLYELYKK  60
   61 VIKRGGYDAV SATEDGWTNI AEEFNQSDPA RSAGILQNVY FKYLISWEIH DHWHLLLPPP 120
  121 STLELSENRQ NVLERV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 32.30103
Match: 1kqqA
Description: DNA-binding domain from the dead ringer protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.55411292098115 bayes_pls_golite062009
DNA binding 4.18200206364084 bayes_pls_golite062009
nucleic acid binding 3.89826332285646 bayes_pls_golite062009
binding 3.49534193682441 bayes_pls_golite062009
transcription factor activity 2.3812627628982 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 2.32480271621458 bayes_pls_golite062009
transcription activator activity 2.19377524406907 bayes_pls_golite062009
transcription coactivator activity 2.08578967307608 bayes_pls_golite062009
transcription factor binding 1.28734696305262 bayes_pls_golite062009
transcription repressor activity 1.17489559520071 bayes_pls_golite062009
transcription cofactor activity 1.13378621684772 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.06026105710513 bayes_pls_golite062009
protein binding 0.923807406971133 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [137-236]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KVFNSCSPPK PTNPITIIDN DKTHSFKKFY KSLVKEDEEN GIEKKINEAM NSSASQPLPN  60
   61 STNFASTTFP SVPFHPLPVD SGLQKYIDRN SNLTPPALGA 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [237-522]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GVPGPPLLVR VALALKSQQD KEVDWAIGHL IKISFERHQE FKLERLPSLA ECLVYSLGFQ  60
   61 VTKAKQVSDL TDISLCMDRA IGIALVLRNS VLSVENAKHV AQTKLVISVL EASIRCAKTF 120
  121 NNLEFLHYCL DISEMISSYL HVEDEKNVFY LALCEFLNSS DYSILIATLR TLARLALNDR 180
  181 NNRLLQDLKS NVIANIIALV ETDNEEIVAA ALDFLYQYTT YRTNTSNLLA SQEAWMLVDQ 240
  241 LIRLMMYQAQ ERFMTVTIEN SESNPAVKHE ATSSISLPME ELQQLV

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.28
Match: 1wa5B
Description: Crystal structure of the exportin Cse1p complexed with its cargo ( Kap60p) and RanGTP
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [523-780]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AMREPERSVK WMRCCFEPSS DDYVLQTDIW QLYCSDMERA QGPNVMGISP ADFIKVSSHA  60
   61 FYNARAMTVS TPQLPVEYVI NGIKRRKFPT SVNGMRYQPC RWCLDSGKEC GELLLGTPLL 120
  121 HSHLQEMHIF PQILETGKCR WSDCKYEIQR LTPASELSHY QLLSHIVTHL HDDSLETLVE 180
  181 GRKLSPSREF RIPLLLTAVD DQGDATGIAL TATLVLRNLV RSKQGKMLFS AIESRVLEVS 240
  241 SLNPAVAPYV SEMLLGQI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 39.69897
Match: 2i13A
Description: No description for 2i13A was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle