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View Structure Prediction Details

Protein: prp17
Organism: Schizosaccharomyces pombe
Length: 558 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for prp17.

Description E-value Query
Range
Subject
Range
gi|186464325, gi... - gi|23128981|ref|ZP_00110817.1| COG2319: FOG: WD40 repeat [Nostoc punctiforme PCC 73102], gi|18668187...
470.0 [0..13] [558..1176]
YY46_NOSS1 - Uncharacterized WD repeat-containing protein alr3466 OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=...
gi|25530855 - pir||AC2239 WD-40 repeat protein [imported] - Nostoc sp. (strain PCC 7120)
457.0 [0..17] [558..956]
gi|35214926, gi|... - gi|37523920|ref|NP_927297.1| WD repeat-containing protein [Gloeobacter violaceus PCC 7421], gi|35214...
455.0 [0..52] [558..570]
gi|75701503, gi|... - gi|75907778|ref|YP_322074.1| ribosome assembly protein 4 (RSA4) [Anabaena variabilis ATCC 29413], gi...
455.0 [0..9] [558..1086]

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Predicted Domain #1
Region A:
Residues: [1-469]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLVANYSSDS EEQENSQSPN IQPLLHTENL APAVVDNVKD DLIVSKGGNS RELARNVPVN  60
   61 EMVQPALGPA NPFVTKEQDS IKNSITGYAE REYVPNFVFN QEYYANTHAI YGKRNFDDNE 120
  121 ATTSTDLKRK SQKIKERRED PGDPSILEGD GAYKGPWAGY GSEQSSSPLE YSEYEEVESL 180
  181 DVKSEKDTES NNLGQNELLK EQLATPEVET HRSKEETILH KDRLFDYQNR SYMHVPNDVG 240
  241 INLSEEPGEQ TCYIPKKHIF TWKGHTKGIS CLRFFPISGH LLLSGSMDNQ IKIWEVYHDR 300
  301 SLLRTFQGHA RPIRDLSFSQ DGRSFLSTSF DKTIKLWDTE LGKCLNCFNS DRLTNCVKFQ 360
  361 VDPDKPNEFL AGTADKRILQ FDIRSPDIVQ AYDHHLGGIN SITFLENGKR FVTTSDDSSM 420
  421 RFWEYGTPVP IKFVADIAMH SMPRVALRPN GKSIACQSLD NCIYVYSAY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 59.154902
Match: 1vyhC
Description: PAF-AH Holoenzyme: Lis1/Alfa2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
6.67009948605948 bayes_pls_golite062009
snoRNA binding 4.78410616474982 bayes_pls_golite062009
histone methyltransferase activity (H3-K4 specific) 4.71992275913384 bayes_pls_golite062009
RNA binding 3.77273677738815 bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity 3.25521258308263 bayes_pls_golite062009
GTPase activity 3.23750443966606 bayes_pls_golite062009
binding 2.42570478946173 bayes_pls_golite062009
protein binding 2.26925404328312 bayes_pls_golite062009
histone methyltransferase activity 1.85632145559025 bayes_pls_golite062009
structural molecule activity 1.47097979074281 bayes_pls_golite062009
protein methyltransferase activity 1.35170368882651 bayes_pls_golite062009
nucleic acid binding 1.2886835964948 bayes_pls_golite062009
cytoskeletal protein binding 1.26395898062853 bayes_pls_golite062009
transcription regulator activity 1.25687092973217 bayes_pls_golite062009
histone-lysine N-methyltransferase activity 1.15313682561559 bayes_pls_golite062009
lysine N-methyltransferase activity 1.15313682561559 bayes_pls_golite062009
protein-lysine N-methyltransferase activity 1.15313682561559 bayes_pls_golite062009
receptor activity 1.12819778129653 bayes_pls_golite062009
G-protein-coupled receptor binding 1.11754260203517 bayes_pls_golite062009
actin binding 1.08902852052152 bayes_pls_golite062009
mRNA binding 1.05053985350578 bayes_pls_golite062009
molecular transducer activity 0.974380908248463 bayes_pls_golite062009
signal transducer activity 0.974380908248463 bayes_pls_golite062009
transporter activity 0.807925044108643 bayes_pls_golite062009
histone binding 0.685319917508843 bayes_pls_golite062009
DNA binding 0.561578774129549 bayes_pls_golite062009
DNA polymerase activity 0.428715007921149 bayes_pls_golite062009
substrate-specific transporter activity 0.414491774707324 bayes_pls_golite062009
transcription factor activity 0.243992994917491 bayes_pls_golite062009
protein kinase activity 0.229242350006544 bayes_pls_golite062009
receptor binding 0.0390635451962911 bayes_pls_golite062009
N-methyltransferase activity 0.00335766408304172 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [470-558]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EKYRQNKKKV FKGYSCSGYS LEVGFSPDGR FVFSGDSSGN ACFWDWKTCK LMAKLPAHSG  60
   61 PVQSMAFHPQ ETSKVATSSI VDGSIKYWD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 61.69897
Match: 2gnqA
Description: No description for 2gnqA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle