YRC Public Data Repository - Protein Structure Prediction

Protein:	SPAPB8E5.07c
Organism:	Schizosaccharomyces pombe
Length:	1163 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAPB8E5.07c.

Description	E-value	Query Range	Subject Range
gi\|11359461, gi\|... - gi\|7800806\|emb\|CAB91265.1\| conserved hypothetical protein [Neurospora crassa], gi\|32415269\|ref\|XP_32... gi\|85082271 - gi\|85082271\|ref\|XP_956881.1\| hypothetical protein NCU01675 [Neurospora crassa OR74A]	1019.0	[0..5]	[1129..4]
RRP12 - Protein required for export of the ribosomal subunits; associates with the RNA components of the pre... RRP12_YEAST - Ribosomal RNA-processing protein 12 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RRP1...	1014.0	[0..8]	[1128..12]
gi\|44985865, gi\|... - gi\|45201082\|ref\|NP_986652.1\| AGL014Cp [Ashbya gossypii ATCC 10895], gi\|44985865\|gb\|AAS54476.1\| AGL01... gi\|44985865 - gi\|44985865\|gb\|AAS54476.1\| AGL014Cp [Ashbya gossypii ATCC 10895]	994.0	[0..8]	[1156..12]
gi\|77022578, gi\|... - gi\|77022578\|ref\|XP_888733.1\| hypothetical protein CaO19_7011 [Candida albicans SC5314], gi\|68471057\|... gi\|76573546 - gi\|76573546\|dbj\|BAE44630.1\| hypothetical protein [Candida albicans]	983.0	[0..8]	[1142..17]
gi\|67540060, gi\|... - gi\|67540060\|ref\|XP_663804.1\| hypothetical protein AN6200.2 [Aspergillus nidulans FGSC A4], ref\|XP_41...	980.0	[0..8]	[1153..4]
gi\|116204877, gi... - gi\|88176450\|gb\|EAQ83918.1\| hypothetical protein CHGG_10322 [Chaetomium globosum CBS 148.51], gi\|1162...	979.0	[0..5]	[1128..3]
gi\|46109342, gi\|... - gi\|46109342\|ref\|XP_381729.1\| hypothetical protein FG01553.1 [Gibberella zeae PH-1], gi\|42545665\|gb\|E...	955.0	[0..5]	[1129..3]
gi\|71001664, gi\|... - gi\|71001664\|ref\|XP_755513.1\| pre-rRNA processing protein Rrp12 [Aspergillus fumigatus Af293], gi\|668... gi\|159129581 - gi\|159129581\|gb\|EDP54695.1\| pre-rRNA processing protein Rrp12, putative [Aspergillus fumigatus A1163...	938.0	[0..8]	[1132..4]
RRP12_MOUSE - RRP12-like protein OS=Mus musculus GN=Rrp12 PE=1 SV=1	928.0	[0..18]	[1151..115]

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Predicted Domain #1

Region A:
Residues: [1-152]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEVNEPLQI ELRKIRNSST AGVINEFDVI VSAVEGTLKE QKTEATPTAY LVALLTLVKE  60
   61 FTDLKKNFKG HTFQLLELVI KYVPSNVLQA KFPQILSVLA PVVNNAETNK TVLLPYLNVL 120
  121 EKLLLLQDYS SWTHGNSCKT SIYILLFFAL SN

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [153-859]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TEKTRVRSLQ ILANILKNPP AGPVTEHPAI KYTAFEPLRL LESLATAKKP KTPAEVQKLN  60
   61 NSLVLIRVLC SSTHWPMTLV ERLCRSCVLI VGQRSTNSIL LVYQILDGLS KKSVDYTDAV 120
  121 SLRMTLICLQ KLEPSEHDPI LMVGWLKAMN TAIRAFNILD KETAKYECLH RFKAFFTLLE 180
  181 SESMEIRLQT ATTICSVIGC LDTTPNSFAV VEEICSFICD ALRDIRFRLA YPECFQIISS 240
  241 LCDKLGPHSD PYLIPALEVI DYLRGSEGFD GKALVDEAIG SFVRAIGPEA MLRVLPLNLE 300
  301 LNDKDAVGRA WLLPVLRDNI RFANLAHFTN YFVPLSGQLY QKVIEMNDLD SIPSKLLQTL 360
  361 VDQIWSLLPG YCYLPLDLQS SFTLEFASIL VNVLYEQVSL RSVICNSLTA LVETNSKVAD 420
  421 KLPLDDVISV PVSASDASSN LAFLTNMSSN FLSVLLNVFS STPSQYRYPI LKCIQTWIFI 480
  481 SSNDTIHSVY KKVTDLLPDS LNDLAGSFNI AADGISSPMA YSLIDLLIVI SPYLNQDYAV 540
  541 TLFEYVHEFL RHVNPAIQKK GYKLLGTLLR VDYGKAYATQ HVKEIFEELS SVADRVVSST 600
  601 RKDRLASLNA LYELQSSELV IAIPQLLPEA IISLKEVNEK ARHTAFQLLF NIAKSAVNSV 660
  661 EFGNSKPERV EKFVSVISAG LAGSSTHMIS ATIIAISSIV MEYKVFI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	8.045757
Match:	2bkuB
Description:	Kap95p:RanGTP complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
RNA binding	3.51706019693543	bayes_pls_golite062009
structural molecule activity	2.89396355704664	bayes_pls_golite062009
protein transporter activity	2.53371837790268	bayes_pls_golite062009
binding	2.47395644967726	bayes_pls_golite062009
protein binding	2.13529412360404	bayes_pls_golite062009
transporter activity	1.75215962704174	bayes_pls_golite062009
nucleic acid binding	1.64539435934931	bayes_pls_golite062009
mRNA binding	1.49239143012448	bayes_pls_golite062009
signal sequence binding	1.46991748555798	bayes_pls_golite062009
substrate-specific transporter activity	1.45007172288203	bayes_pls_golite062009
nuclear localization sequence binding	1.27627067567874	bayes_pls_golite062009
transcription regulator activity	1.06250847754412	bayes_pls_golite062009
DNA binding	0.946847037737779	bayes_pls_golite062009
protein transmembrane transporter activity	0.58863391569272	bayes_pls_golite062009
transmembrane transporter activity	0.506596930838594	bayes_pls_golite062009
nuclear export signal receptor activity	0.501965300276747	bayes_pls_golite062009
transcription factor activity	0.362911773502049	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.229272703956702	bayes_pls_golite062009
cytoskeletal protein binding	0.0330689772947346	bayes_pls_golite062009
nucleoside-triphosphatase activity	0.00566872062869428	bayes_pls_golite062009

Predicted Domain #3

Region A:
Residues: [860-973]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SEPFLVQLIS TLNLFITSSK REIAKAAIDF IKISVSSFPV ECIKPLLPEL IPNLLAWSHE  60
   61 GKANLRVKVR HLFEKMGRKY GIAEIEPFFP AEDKKLITNI RKTQERNIRK RAMK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	38.0
Match:	1u6gC
Description:	Crystal Structure of The Cand1-Cul1-Roc1 Complex
Matching Structure (courtesy of the PDB):

Predicted Domain #4

Region A:
Residues: [974-1163]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RDPAKPSSAQ PRKTFASAYE AAVYDTDDEA EEEFENDEMN NGNGGDLRMD EAFVQEDNDE  60
   61 EPLDLLDIEA VSKISSTDPR KKLAARKQKL NSAFKSNEEG RLLINDSDED ELIEDSLANA 120
  121 QQHAEVNRTY LEAVAGKESF RRGLNNRVKF SNKRVRDDYD EEMEEVEVPE VTRKPAKQKF 180
  181 DRKQRGQKGY

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: