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View Structure Prediction Details

Protein: cnp1
Organism: Schizosaccharomyces pombe
Length: 120 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cnp1.

Description E-value Query
Range
Subject
Range
gi|88943485 - gi|88943485|ref|XP_497711.2| PREDICTED: similar to H3 histone, family 2 isoform 2 [Homo sapiens]
194.0 [0..2] [119..70]
gi|76612880 - gi|76612880|ref|XP_871849.1| PREDICTED: similar to H3 histone, family 2 isoform 2 [Bos taurus]
189.0 [0..2] [119..232]
gi|50728592 - gi|50728592|ref|XP_416193.1| PREDICTED: similar to histone protein Hist2h3c1 [Gallus gallus]
187.0 [0..2] [119..646]
gi|116057937 - gi|116057937|emb|CAL54140.1| Histones H3 and H4 (ISS) [Ostreococcus tauri]
187.0 [0..2] [119..56]
gi|74003971, gi|... - gi|74003975|ref|XP_859248.1| PREDICTED: similar to histone 1, H2ai (predicted) isoform 3 [Canis fami...
185.0 [0..2] [119..26]
gi|148706930, gi... - gi|62739244|gb|AAH94041.1| Histone cluster 2, H3c1 [Mus musculus], gi|30061401|ref|NP_835734.1| hist...
183.0 [0..2] [119..71]
gi|77548740, gi|... - gi|77548740|gb|ABA91537.1| histone H3 [Oryza sativa (japonica cultivar-group)], gi|62701879|gb|AAX92...
183.0 [0..2] [119..26]

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Predicted Domain #1
Region A:
Residues: [1-120]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKKSLMAEP GDPIPRPRKK RYRPGTTALR EIRKYQRSTD LLIQRLPFSR IVREISSEFV  60
   61 ANFSTDVGLR WQSTALQCLQ EAAEAFLVHL FEDTNLCAIH AKRVTIMQRD MQLARRIRGA 120
  121 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 45.39794
Match: 1aoiA
Description: Histone H3
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
general RNA polymerase II transcription factor activity 4.57339366278729 bayes_pls_golite062009
DNA binding 4.49118409263799 bayes_pls_golite062009
nucleic acid binding 4.35201412176948 bayes_pls_golite062009
transcription regulator activity 4.08606081850613 bayes_pls_golite062009
binding 3.27510691458843 bayes_pls_golite062009
centromeric DNA binding 2.60445660474495 bayes_pls_golite062009
transcription factor activity 2.51581622888695 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.38228606466152 bayes_pls_golite062009
transcription repressor activity 2.3574713307436 bayes_pls_golite062009
transcription corepressor activity 1.30859203490073 bayes_pls_golite062009
transcription activator activity 1.25487495162413 bayes_pls_golite062009
transcription factor binding 1.15204005455906 bayes_pls_golite062009
protein binding 1.07873333188144 bayes_pls_golite062009
transcription cofactor activity 1.01502031330902 bayes_pls_golite062009
transcription initiation factor activity 0.725138319268162 bayes_pls_golite062009
histone binding 0.218942897869955 bayes_pls_golite062009
transcription coactivator activity 0.0885263144317296 bayes_pls_golite062009
sequence-specific DNA binding 0.0852726470007639 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
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