YRC Public Data Repository - Protein Structure Prediction

Protein:	SPBC16E9.14c
Organism:	Schizosaccharomyces pombe
Length:	386 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC16E9.14c.

Description	E-value	Query Range	Subject Range
gi\|74000518 - gi\|74000518\|ref\|XP_544664.2\| PREDICTED: similar to solute carrier family 30 (zinc transporter), memb...	227.0	[0..18]	[384..180]
CE03664 - WBGene00011821 cobalt uptake like protein status:Predicted TR:Q22541 protein_id:CAA92193.1	217.0	[0..72]	[384..55]
MTP3_ORYSJ - Metal tolerance protein 3 OS=Oryza sativa subsp. japonica GN=MTP3 PE=2 SV=1	215.0	[0..2]	[385..18]
CG31860-PA - This gene is referred to in FlyBase by the symbol Dmel\CG31860 (CG31860, FBgn0051860). It is a prote...	214.0	[0..8]	[384..215]
gi\|76611372 - gi\|76611372\|ref\|XP_588317.2\| PREDICTED: similar to PP12488 [Bos taurus]	213.0	[0..67]	[384..282]
gi\|114656820 - gi\|114656820\|ref\|XP_510375.2\| PREDICTED: solute carrier family 30 (zinc transporter), member 4 isofo...	212.0	[0..18]	[384..24]
ZNT4_RAT - Zinc transporter 4 OS=Rattus norvegicus GN=Slc30a4 PE=2 SV=1	212.0	[0..18]	[384..24]
ZNT2_MOUSE - Zinc transporter 2 OS=Mus musculus GN=Slc30a2 PE=2 SV=1	212.0	[0..67]	[385..45]
gi\|123982612 - gi\|123982612\|gb\|ABM83047.1\| solute carrier family 30 (zinc transporter), member 4 [synthetic constru... SLC30A4 - solute carrier family 30 (zinc transporter), member 4	211.0	[0..18]	[384..24]

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Predicted Domain #1

Region A:
Residues: [1-87]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTQNHNIPTA IQIQNPINNN VSVTISDQLP KPSANNPNLL SVDTRPTHRK GHHHKHSLSH  60
   61 QYFLPPKNRQ PLEIPASYPI PTFKETF

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.507	a.28.1	ACP-like
View	Download	0.384	b.82.3	cAMP-binding domain-like
View	Download	0.262	a.76.1	Iron-dependent represor protein, dimerization domain
View	Download	0.231	a.77.1	DEATH domain

Predicted Domain #2

Region A:
Residues: [88-386]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AILTFPQKLK LTSSILFFLV AVGVLLSGDA TILLTLSCSL IVEGVLIIIN VWRETLDSFL  60
   61 VWRHTCLRYP FGMQQMELLV DFSFSILLIF LGMNLLKEPA EHAIEDWGNL HHAGDHEEET 120
  121 VHIHLTISLF ASAIISGFAL LLDHPSAHIR ELNSRFFHGL TLVPSLILVL LLSLGYQVGS 180
  181 FLSHLLSLTI AVTALVNGFS IAKSLALMLL LTYSNKEKVF ECVSLIKEDT RIDQLNYAAI 240
  241 WQPHYNTCIA NIGLTVSGGE REQAAVREDI IRIIQKTVGS IFGAGVQPKW EISVDIQRA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	48.69897
Match:	2qfiA
Description:	No description for 2qfiA was found.

Predicted functions:

Term	Confidence	Notes
cation transmembrane transporter activity	6.3253503604398	bayes_pls_golite062009
ion transmembrane transporter activity	6.22189384650962	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	5.82185991246167	bayes_pls_golite062009
transporter activity	4.27173462293249	bayes_pls_golite062009
transmembrane transporter activity	4.18558383943492	bayes_pls_golite062009
substrate-specific transporter activity	3.94511592355578	bayes_pls_golite062009
metal ion transmembrane transporter activity	2.43294134632841	bayes_pls_golite062009
transition metal ion transmembrane transporter activity	2.32644140472297	bayes_pls_golite062009
efflux transmembrane transporter activity	1.98656970252979	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	1.95281540802467	bayes_pls_golite062009
binding	1.70389974039196	bayes_pls_golite062009
cation channel activity	1.55011961058299	bayes_pls_golite062009
di-, tri-valent inorganic cation transmembrane transporter activity	1.31663166812163	bayes_pls_golite062009
ion channel activity	1.01093555209783	bayes_pls_golite062009
passive transmembrane transporter activity	0.963824080292546	bayes_pls_golite062009
channel activity	0.963824080292546	bayes_pls_golite062009
substrate-specific channel activity	0.948079854416241	bayes_pls_golite062009
cadmium ion transmembrane transporter activity	0.661906409169955	bayes_pls_golite062009
active transmembrane transporter activity	0.490905558612378	bayes_pls_golite062009
iron ion transmembrane transporter activity	0.376948884172728	bayes_pls_golite062009
protein binding	0.311357063667067	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: