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View Structure Prediction Details

Protein: ubx2
Organism: Schizosaccharomyces pombe
Length: 427 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ubx2.

Description E-value Query
Range
Subject
Range
gi|50752130 - gi|50752130|ref|XP_422667.1| PREDICTED: similar to KIAA0794 protein [Gallus gallus]
212.0 [0..6] [424..864]
PUX7_ARATH - Plant UBX domain-containing protein 7 OS=Arabidopsis thaliana GN=PUX7 PE=1 SV=1
206.0 [0..2] [427..7]
gi|74002808 - gi|74002808|ref|XP_545151.2| PREDICTED: similar to CG8892-PA, isoform A isoform 1 [Canis familiaris]
205.0 [0..2] [424..10]
gi|55725779 - gi|55725779|emb|CAH89670.1| hypothetical protein [Pongo abelii]
gi|55725779|emb|... - hypothetical protein [Pongo pygmaeus]
205.0 [0..2] [424..10]
gi|3882309 - gi|3882309|dbj|BAA34514.1| KIAA0794 protein [Homo sapiens]
204.0 [0..2] [424..11]
gi|74188735, gi|... - gi|74188735|dbj|BAE28100.1| unnamed protein product [Mus musculus], gi|226958595|ref|NP_808301.2| UB...
203.0 [0..2] [424..10]
gi|34869261, gi|... - ref|XP_221375.2| similar to KIAA0794 protein [Rattus norvegicus], gi|149060711|gb|EDM11425.1| rCG526...
201.0 [0..6] [424..15]
gi|58390101, gi|... - gi|58390101|ref|XP_317491.2| AGAP007977-PA [Anopheles gambiae str. PEST], gi|55237707|gb|EAA12408.2|...
AGAP007977-PA - Fas-associated factor|protein_coding|3R:3624887:3626278:1|gene:AGAP007977
197.0 [0..1] [424..6]

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Predicted Domain #1
Region A:
Residues: [1-60]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDGDEASLVA NFCAITNSTP EKAQEYLSVA DGDLSTAITL FFESGGVTDV QSSYIEAPSQ  60
   61 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.0
Match: 2damA
Description: No description for 2damA was found.

Predicted Domain #2
Region A:
Residues: [61-148]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TEPVEEIRAP IAPTREVLVD PLADMSAGTS IMGNNFGFGG FPRMNRRQRR RMGIFDQSPS  60
   61 QIPFPSSNTE DSSEESDSSS RASRLAKL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [149-279]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FRPPYDIISN LSLDEARIEA SSQKRWILVN LQTSTSFECQ VLNRDLWKDE SVKEVIRAHF  60
   61 LFLQLLDDEE PGMEFKRFYP VRSTPHIAIL DPRTGERVKE WSKSFTPADF VIALNDFLEG 120
  121 CTLDETSGRK N

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.045757
Match: 2dlxA
Description: No description for 2dlxA was found.

Predicted functions:

Term Confidence Notes
catalytic activity 0.672192331361968 bayes_pls_golite062009
binding 0.665189138843282 bayes_pls_golite062009
hydrolase activity 0.150237022038507 bayes_pls_golite062009
transcription regulator activity 0.13699526678272 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [280-427]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLGAKSQKPV EAMSEDEQMH KAIAASLGNG NSTTESQGES SSQQAESHGV ADDTVHKIDS  60
   61 AECDAEEPSP GPNVTRIQIR MPNGARFIRR FSLTDPVSKV YAYVKGVAEG ADKQPFSLTF 120
  121 QRKSLWTSLD STIKEAGIQN TALQFEFQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.0
Match: 1s3sG
Description: Crystal structure of AAA ATPase p97/VCP ND1 in complex with p47 C
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.19381585790185 bayes_pls_golite062009
small conjugating protein ligase activity 1.83465130904364 bayes_pls_golite062009
protein binding 1.17197911794381 bayes_pls_golite062009
ubiquitin-protein ligase activity 1.16468510691469 bayes_pls_golite062009
acid-amino acid ligase activity 0.919595189902044 bayes_pls_golite062009
nucleic acid binding 0.383121378043805 bayes_pls_golite062009
hydrolase activity 0.247201449341942 bayes_pls_golite062009
DNA binding 0.0840213088061073 bayes_pls_golite062009
transcription regulator activity 0.0485636215870291 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle