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View Structure Prediction Details

Protein: ubx2
Organism: Schizosaccharomyces pombe
Length: 427 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ubx2.

Description E-value Query
Range
Subject
Range
gi|50752130 - gi|50752130|ref|XP_422667.1| PREDICTED: similar to KIAA0794 protein [Gallus gallus]
212.0 [0..6] [424..864]
PUX7_ARATH - Plant UBX domain-containing protein 7 OS=Arabidopsis thaliana GN=PUX7 PE=1 SV=1
206.0 [0..2] [427..7]
gi|74002808 - gi|74002808|ref|XP_545151.2| PREDICTED: similar to CG8892-PA, isoform A isoform 1 [Canis familiaris]
205.0 [0..2] [424..10]
gi|55725779 - gi|55725779|emb|CAH89670.1| hypothetical protein [Pongo abelii]
gi|55725779|emb|... - hypothetical protein [Pongo pygmaeus]
205.0 [0..2] [424..10]
gi|3882309 - gi|3882309|dbj|BAA34514.1| KIAA0794 protein [Homo sapiens]
204.0 [0..2] [424..11]
gi|74188735, gi|... - gi|74188735|dbj|BAE28100.1| unnamed protein product [Mus musculus], gi|226958595|ref|NP_808301.2| UB...
203.0 [0..2] [424..10]
gi|34869261, gi|... - ref|XP_221375.2| similar to KIAA0794 protein [Rattus norvegicus], gi|149060711|gb|EDM11425.1| rCG526...
201.0 [0..6] [424..15]
gi|58390101, gi|... - gi|58390101|ref|XP_317491.2| AGAP007977-PA [Anopheles gambiae str. PEST], gi|55237707|gb|EAA12408.2|...
AGAP007977-PA - Fas-associated factor|protein_coding|3R:3624887:3626278:1|gene:AGAP007977
197.0 [0..1] [424..6]

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Predicted Domain #1
Region A:
Residues: [1-60]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDGDEASLVA NFCAITNSTP EKAQEYLSVA DGDLSTAITL FFESGGVTDV QSSYIEAPSQ  60
   61 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.0
Match: 2damA
Description: No description for 2damA was found.

Predicted Domain #2
Region A:
Residues: [61-148]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TEPVEEIRAP IAPTREVLVD PLADMSAGTS IMGNNFGFGG FPRMNRRQRR RMGIFDQSPS  60
   61 QIPFPSSNTE DSSEESDSSS RASRLAKL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [149-279]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FRPPYDIISN LSLDEARIEA SSQKRWILVN LQTSTSFECQ VLNRDLWKDE SVKEVIRAHF  60
   61 LFLQLLDDEE PGMEFKRFYP VRSTPHIAIL DPRTGERVKE WSKSFTPADF VIALNDFLEG 120
  121 CTLDETSGRK N

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.045757
Match: 2dlxA
Description: No description for 2dlxA was found.

Predicted functions:

Term Confidence Notes
catalytic activity 0.672192331361968 bayes_pls_golite062009
binding 0.665189138843282 bayes_pls_golite062009
hydrolase activity 0.150237022038507 bayes_pls_golite062009
transcription regulator activity 0.13699526678272 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [280-427]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLGAKSQKPV EAMSEDEQMH KAIAASLGNG NSTTESQGES SSQQAESHGV ADDTVHKIDS  60
   61 AECDAEEPSP GPNVTRIQIR MPNGARFIRR FSLTDPVSKV YAYVKGVAEG ADKQPFSLTF 120
  121 QRKSLWTSLD STIKEAGIQN TALQFEFQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.0
Match: 1s3sG
Description: Crystal structure of AAA ATPase p97/VCP ND1 in complex with p47 C
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.19381585790185 bayes_pls_golite062009
small conjugating protein ligase activity 1.83465130904364 bayes_pls_golite062009
protein binding 1.17197911794381 bayes_pls_golite062009
ubiquitin-protein ligase activity 1.16468510691469 bayes_pls_golite062009
acid-amino acid ligase activity 0.919595189902044 bayes_pls_golite062009
nucleic acid binding 0.383121378043805 bayes_pls_golite062009
hydrolase activity 0.247201449341942 bayes_pls_golite062009
DNA binding 0.0840213088061073 bayes_pls_golite062009
transcription regulator activity 0.0485636215870291 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle