YRC Public Data Repository - Protein Structure Prediction

Protein:	mtf1
Organism:	Schizosaccharomyces pombe
Length:	366 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mtf1.

Description	E-value	Query Range	Subject Range
gi\|32034722 - gi\|32034722\|ref\|ZP_00134853.1\| COG0030: Dimethyladenosine transferase (rRNA methylation) [Actinobaci... RSMA_ACTP2 - Ribosomal RNA small subunit methyltransferase A OS=Actinobacillus pleuropneumoniae serotype 5b (stra...	292.0	[0..22]	[365..7]
gi\|227175834, gi... - gi\|227555047\|ref\|ZP_03985094.1\| dimethyladenosine transferase [Enterococcus faecalis HH22], gi\|22717... RSMA_ENTFA - Ribosomal RNA small subunit methyltransferase A OS=Enterococcus faecalis (strain ATCC 700802 / V583)... gi\|227074699, gi... - gi\|227517856\|ref\|ZP_03947905.1\| dimethyladenosine transferase [Enterococcus faecalis TX0104], gi\|227... KSGA_ENTFA, RSMA... - Ribosomal RNA small subunit methyltransferase A OS=Enterococcus faecalis GN=rsmA PE=3 SV=1, Dimethyl... gi\|238829852, gi... - gi\|238857491\|ref\|ZP_04647727.1\| dimethyladenosine transferase [Enterococcus faecalis TUSoD Ef11], gi...	286.0	[0..12]	[350..7]
gi\|25286079, gi\|... - gi\|25286080\|pir\|\|AF2712 rRNA-adenine N6,N6-dimethyltransferase [imported] - Agrobacterium tumefacien... RSMA_AGRFC - Ribosomal RNA small subunit methyltransferase A OS=Agrobacterium fabrum (strain C58 / ATCC 33970) GN...	286.0	[0..10]	[348..2]
RSMA_HAEDU, KSGA... - Ribosomal RNA small subunit methyltransferase A OS=Haemophilus ducreyi GN=rsmA PE=3 SV=1, Dimethylad... RSMA_HAEDU - Ribosomal RNA small subunit methyltransferase A OS=Haemophilus ducreyi (strain 35000HP / ATCC 700724...	284.0	[0..17]	[364..2]
KSGA_PASMU, RSMA... - Ribosomal RNA small subunit methyltransferase A OS=Pasteurella multocida GN=rsmA PE=3 SV=1, Dimethyl... RSMA_PASMU - Ribosomal RNA small subunit methyltransferase A OS=Pasteurella multocida (strain Pm70) GN=rsmA PE=3 ...	283.0	[0..22]	[363..4]
gi\|145635368, gi... - gi\|145635368\|ref\|ZP_01791070.1\| dimethyladenosine transferase [Haemophilus influenzae PittAA], gi\|14... RSMA_HAEI8 - Ribosomal RNA small subunit methyltransferase A OS=Haemophilus influenzae (strain 86-028NP) GN=rsmA ...	282.0	[0..22]	[365..4]
RSMA_HAEIN, KSGA... - Ribosomal RNA small subunit methyltransferase A OS=Haemophilus influenzae GN=rsmA PE=3 SV=1, Dimethy... RSMA_HAEIN - Ribosomal RNA small subunit methyltransferase A OS=Haemophilus influenzae (strain ATCC 51907 / DSM 1... gi\|145628930, gi... - gi\|145628930\|ref\|ZP_01784730.1\| dimethyladenosine transferase [Haemophilus influenzae 22.1-21], gi\|1...	282.0	[0..22]	[365..4]
gi\|134297956, gi... - gi\|88947021\|ref\|ZP_01150050.1\| RRNA 16S rRNA dimethylase [Desulfotomaculum reducens MI-1], gi\|889235...	281.0	[0..12]	[351..4]
gi\|229846634, gi... - gi\|229846634\|ref\|ZP_04466742.1\| dimethyladenosine transferase [Haemophilus influenzae 7P49H1], gi\|22... gi\|229845712, gi... - gi\|229845712\|ref\|ZP_04465834.1\| dimethyladenosine transferase [Haemophilus influenzae 6P18H1], gi\|22... gi\|42629998 - gi\|42629998\|ref\|ZP_00155543.1\| COG0030: Dimethyladenosine transferase (rRNA methylation) [Haemophilu... RSMA_HAEIG - Ribosomal RNA small subunit methyltransferase A OS=Haemophilus influenzae (strain PittGG) GN=rsmA PE... RSMA_HAEIE - Ribosomal RNA small subunit methyltransferase A OS=Haemophilus influenzae (strain PittEE) GN=rsmA PE...	281.0	[0..22]	[365..4]
RSMA_SINMW - Ribosomal RNA small subunit methyltransferase A OS=Sinorhizobium medicae (strain WSM419) GN=rsmA PE=...	279.0	[0..10]	[348..2]

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Predicted Domain #1

Region A:
Residues: [1-366]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLPKILYDA AAFGGPRSTG FVKILNLNGR SSYKSSYLVN QNLMDEALVK SNLLKEYNSE  60
   61 KMTILEMAPG PGVTTTSLFN YFQPKSHVVL ESREVFSKPL QKLCTLSDGR IKWVHQDGYY 120
  121 WQTYEDVYVS KVLDPRIQTE EEQKLSPHRE LLFFAHLPHG YAGLLFVSQI LDFLSARDWL 180
  181 GIFGRVRVLL WLPCSPTVTL LGSRGFSKRS KTSVFREAFT DSRVLAASES TLQKLCMGYS 240
  241 KEAKENYQIS PNPLLVSPTP ITSEPHKEDL TLVEMCSKPQ DKQLSIPVFE SIVRILLTCK 300
  301 ATSLSKSIYY LGPGAETLLP SFTQCGINID MPVGLLSAAD FLTISKIIQK YPFKHHLHLG 360
  361 TIIEDS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	53.154902
Match:	1i4wA
Description:	Transcription factor sc-mtTFB
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
mitochondrial transcription initiation factor activity	5.78749963618564	bayes_pls_golite062009
transferase activity	5.03626224752203	bayes_pls_golite062009
transcription regulator activity	1.42049721553167	bayes_pls_golite062009
catalytic activity	1.25333584501255	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	1.07629237539972	bayes_pls_golite062009
binding	1.06990970478592	bayes_pls_golite062009
methyltransferase activity	1.06467956103007	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	1.04881630872808	bayes_pls_golite062009
DNA binding	1.03011331296251	bayes_pls_golite062009
nucleic acid binding	0.718731143662013	bayes_pls_golite062009
N-methyltransferase activity	0.619676326387443	bayes_pls_golite062009
protein methyltransferase activity	0.527930488619791	bayes_pls_golite062009
RNA methyltransferase activity	0.473668177706488	bayes_pls_golite062009
transcription factor binding	0.149382105526243	bayes_pls_golite062009
protein binding	0.0283208412023089	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: