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View Structure Prediction Details

Protein: SPAC1399.05c
Organism: Schizosaccharomyces pombe
Length: 529 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC1399.05c.

Description E-value Query
Range
Subject
Range
gi|42552011, gi|... - gi|46121217|ref|XP_385163.1| hypothetical protein FG04987.1 [Gibberella zeae PH-1], gi|42552011|gb|E...
224.0 [0..2] [497..31]
gi|67524611, gi|... - gi|67524611|ref|XP_660367.1| hypothetical protein AN2763.2 [Aspergillus nidulans FGSC A4], ref|XP_40...
221.0 [0..132] [518..140]
gi|114189297, gi... - gi|115402749|ref|XP_001217451.1| conserved hypothetical protein [Aspergillus terreus NIH2624], gi|11...
188.0 [0..132] [518..244]
gi|70999243, gi|... - gi|70999243|ref|XP_754343.1| C6 transcription factor [Aspergillus fumigatus Af293], gi|66851980|gb|E...
183.0 [0..134] [508..225]
gi|169763794 - gi|169763794|ref|XP_001727797.1| hypothetical protein [Aspergillus oryzae RIB40]
gi|83770825 - gi|83770825|dbj|BAE60958.1| unnamed protein product [Aspergillus oryzae]
180.0 [0..230] [510..27]

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Predicted Domain #1
Region A:
Residues: [1-118]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGEVERTRQS SSSLLTFKRK RALEACDSCR KQKTRCLAGS VEDENRACLR CRSLNMDCSL  60
   61 ADPNHFIRKV ENDNMDAISA NINSKLENRL KVLEKAISSI TNSPIAGQIS LKSEKDVF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.154902
Match: 2er8A
Description: No description for 2er8A was found.

Predicted Domain #2
Region A:
Residues: [119-183]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LQGLLSMDEI ELLLEIFIER YGKRWLSVDY SASQYMELLY TKSHLMLATA CLIALRHNPS  60
   61 LKARI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [184-529]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YTDVLNIVDR LISEELLTTS PSLQFFEAVS MLTLYRPLRL SQKQDLWLLS GFALQHRTLS  60
   61 STKGWFNGFA GSSATLTYLD IVPARTWNHL CHGHLVMCMG YRRHAMLDEN TFDDCRNILT 120
  121 NTKANEFDGN ILGMLSVYSM LYRMLRSPTL DLDYAIFQLE EWRKEWCHLW EQPEPQYSRI 180
  181 AYFYSYNVVY EASIQTATDG NDFANIPRYV SMVQSYALKT IDAIFELSAY DMSRCSDHVL 240
  241 FHAGFASASL LRLIYAAKTK EVDTSIVQPK VLNDLVTKIW KWLLVISVDQ YHLATKFANY 300
  301 LKEYQKTVNE GTAESTWFKG PLRPVSSTTL QALKPYNLGV ATVERG

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.02
Match: 1kxuA
Description: CYCLIN H, A POSITIVE REGULATORY SUBUNIT OF CDK ACTIVATING KINASE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 2.75688185850223 bayes_pls_golite062009
binding 2.37916921859542 bayes_pls_golite062009
nucleic acid binding 2.06743451505655 bayes_pls_golite062009
DNA binding 1.95321993038755 bayes_pls_golite062009
cyclin-dependent protein kinase regulator activity 1.41497909264171 bayes_pls_golite062009
protein binding 1.37207701115974 bayes_pls_golite062009
transcription factor activity 1.22628491144894 bayes_pls_golite062009
protein kinase regulator activity 1.21941169140389 bayes_pls_golite062009
kinase regulator activity 1.18590233040331 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.962670695182671 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.797465164318676 bayes_pls_golite062009
transcription factor binding 0.655253705928308 bayes_pls_golite062009
enzyme regulator activity 0.461517963237846 bayes_pls_golite062009
transcription activator activity 0.0606514459376675 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle