YRC Public Data Repository - Protein Structure Prediction

Protein:	SPAC7D4.12c
Organism:	Schizosaccharomyces pombe
Length:	759 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC7D4.12c.

Description	E-value	Query Range	Subject Range
gi\|45198593, gi\|... - gi\|45198593\|ref\|NP_985622.1\| AFR075Cp [Ashbya gossypii ATCC 10895], gi\|44984544\|gb\|AAS53446.1\| AFR07... PRM10_ASHGO - Pheromone-regulated membrane protein 10 OS=Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 99...	442.0	[0..2]	[758..4]
gi\|76573627 - gi\|76573627\|dbj\|BAE44711.1\| hypothetical protein [Candida albicans] PRM10_CANAW - Pheromone-regulated membrane protein 10 OS=Candida albicans (strain WO-1) GN=CAWG_05545 PE=3 SV=1 PRM10_CANAL - Pheromone-regulated membrane protein 10 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PRM10...	431.0	[0..114]	[757..393]
PRM10_MILFA - Pheromone-regulated membrane protein 10 OS=Millerozyma farinosa PE=3 SV=1	428.0	[0..110]	[758..12]
gi\|40747961, gi\|... - gi\|67903016\|ref\|XP_681764.1\| hypothetical protein AN8495.2 [Aspergillus nidulans FGSC A4], ref\|XP_41...	408.0	[0..6]	[759..67]
gi\|70985921, gi\|... - gi\|70985921\|ref\|XP_748465.1\| DUF1212 domain membrane protein [Aspergillus fumigatus Af293], gi\|66846...	390.0	[0..68]	[755..253]
gi\|49644343\|emb\|... - unnamed protein product [Kluyveromyces lactis NRRL Y-1140] PRM10_KLULA - Pheromone-regulated membrane protein 10 OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 7...	382.0	[0..86]	[758..290]
gi\|49653492, gi\|... - gi\|50418615\|ref\|XP_457826.1\| hypothetical protein DEHA0C03817g [Debaryomyces hansenii CBS767], gi\|49...	379.0	[0..215]	[758..461]
gi\|49525860 - gi\|49525860\|emb\|CAG59479.1\| unnamed protein product [Candida glabrata] PRM10_CANGA - Pheromone-regulated membrane protein 10 OS=Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 /...	379.0	[0..282]	[758..313]
gi\|115387627, gi... - gi\|115387627\|ref\|XP_001211319.1\| conserved hypothetical protein [Aspergillus terreus NIH2624], gi\|11...	369.0	[0..58]	[759..113]

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Predicted Domain #1

Region A:
Residues: [1-116]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDGNRRVRFN TDRRPYLSPL QTSFPSSTSF QTPTFLIEED DEDTEDDDGP QVLPVHRAPS  60
   61 PAAFRKRGSI TSMDQYLVNM PAVPSPTASK VGLLDARNTD VESYAASYKT QSSSNS

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [117-313]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VNSLPMRRPT LDRSYSAPMI AAKNLQSDPE KMSNVESTNE LPSTTTEAYK LVAAHTAARL  60
   61 EHMRLNALKA ANDEGEDVKD NEQDDNIDES DPFANPKASY RGGVLSNLLK LYTNSNTVTS 120
  121 SRISLKHTDP TKWQKHAKRT ASSNSLTDLL HASNQTFMAP ASGLQSTEEI PQFSKTGHSR 180
  181 GRKFNFHHHS RKNSGLN

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [314-416]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EEYKITIHLA DILQRQKYIL KLCRALMVYG APSHRLEEHM ASAAKVLEIE GQFLYIPGCM  60
   61 IVSFGDVNTH TSDMHIVRVN QTIDLGRLKL VHDIYKAVLH DRM

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.876	0.839	endoplasmic reticulum	d.110.4	SNARE-like

Predicted Domain #4

Region A:
Residues: [417-759]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GVEEAIRGLD EIFKSPPYFR TWILVVFYGF ASATILPMSF QGGWIDLPIA FILGCLVGIL  60
   61 QHYIAPRSTM YNSLFEVTGS IITSFLSRAF GSIRYSGGRR FCFSALAEGA IVLILPGYIV 120
  121 LCGSLELQSK NIVAGGVRMF YAIIYSLFLS FGISIGAALY GWMDHNATDS TSCPVSTQMD 180
  181 DKWKILFVPL FTLCLLIVNQ ARPSQWPVSI FISCAGYVVN YFTAKHFGSN PIANAIGSFA 240
  241 IGCLGNIYSR LGRGVAFAAV LPAIFVQVPS GLAAQGGISS GIEVATSLTN NTYNTSSSST 300
  301 LDVNSLKFGL VMVQIAIGIS VGLFASALVV YPFGKRRSGL FSF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	66.0
Match:	2nuuA
Description:	No description for 2nuuA was found.

Predicted functions:

Term	Confidence	Notes
cation transmembrane transporter activity	3.37551746791562	bayes_pls_golite062009
ion transmembrane transporter activity	2.46309977364589	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	2.43363909456767	bayes_pls_golite062009
organic cation transmembrane transporter activity	2.28889582696925	bayes_pls_golite062009
ammonium transmembrane transporter activity	2.28258580483562	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	2.24340667591076	bayes_pls_golite062009
substrate-specific transporter activity	2.13062477643948	bayes_pls_golite062009
transmembrane transporter activity	1.91632548941379	bayes_pls_golite062009
transporter activity	1.87457067022308	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: