YRC Public Data Repository - Protein Structure Prediction

Protein:	SPCC965.04c
Organism:	Schizosaccharomyces pombe
Length:	709 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPCC965.04c.

Description	E-value	Query Range	Subject Range
gi\|73541858, gi\|... - gi\|73541858\|ref\|YP_296378.1\| peptidase M41, FtsH [Ralstonia eutropha JMP134], gi\|72119271\|gb\|AAZ6153...	461.0	[0..210]	[709..97]
gi\|21107929, gi\|... - gi\|21242481\|ref\|NP_642063.1\| cell division protein [Xanthomonas axonopodis pv. citri str. 306], gi\|2...	459.0	[0..123]	[708..27]
gi\|78035751, gi\|... - gi\|78047321\|ref\|YP_363496.1\| cell division protein FtsH (ATP-dependent zinc metallopeptidase) [Xanth...	458.0	[0..123]	[708..27]
gi\|170729313, gi... - gi\|170729313\|ref\|YP_001774746.1\| cell division protein [Xylella fastidiosa M12], gi\|167964106\|gb\|ACA... gi\|71275933, gi\|... - gi\|71275933\|ref\|ZP_00652216.1\| Peptidase M41, FtsH [Xylella fastidiosa Dixon], gi\|71163310\|gb\|EAO130... gi\|71730229, gi\|... - gi\|71900019\|ref\|ZP_00682164.1\| Peptidase M41, FtsH [Xylella fastidiosa Ann-1], gi\|71730229\|gb\|EAO323...	457.0	[0..222]	[708..120]
gi\|9104871, gi\|1... - gi\|9104871\|gb\|AAF82906.1\|AE003863_8 cell division protein [Xylella fastidiosa 9a5c], gi\|15836698\|ref... gi\|11278955 - pir\|\|C82849 cell division protein XF0093 [imported] - Xylella fastidiosa (strain 9a5c)	457.0	[0..222]	[708..120]
gi\|120556262, gi... - gi\|77955024\|ref\|ZP_00819404.1\| Peptidase M41, FtsH [Marinobacter aquaeolei VT8], gi\|77866069\|gb\|EAO9...	457.0	[0..222]	[706..111]
gi\|76884341, gi\|... - gi\|77166027\|ref\|YP_344552.1\| peptidase M41, FtsH [Nitrosococcus oceani ATCC 19707], gi\|76884341\|gb\|A...	457.0	[0..217]	[706..106]
gi\|28871631, gi\|... - gi\|28871631\|ref\|NP_794250.1\| cell division protein FtsH [Pseudomonas syringae pv. tomato str. DC3000... tr\|Q87WP8\|Q87WP8... - ATP-dependent zinc metalloprotease FtsH OS=Pseudomonas syringae pv. tomato (strain DC3000) GN=ftsH P...	457.0	[0..144]	[708..32]
gi\|28198007, gi\|... - gi\|28198007\|ref\|NP_778321.1\| cell division protein [Xylella fastidiosa Temecula1], gi\|28056067\|gb\|AA... gi\|71899229, gi\|... - gi\|71899229\|ref\|ZP_00681391.1\| Peptidase M41, FtsH [Xylella fastidiosa Ann-1], gi\|71730962\|gb\|EAO330... gi\|182630743, gi... - gi\|182680633\|ref\|YP_001828793.1\| ATP-dependent metalloprotease FtsH [Xylella fastidiosa M23], gi\|182...	457.0	[0..222]	[708..120]
gi\|91688491, gi\|... - gi\|91784537\|ref\|YP_559743.1\| FtsH peptidase [Burkholderia xenovorans LB400], gi\|91688491\|gb\|ABE31691...	457.0	[0..210]	[706..97]

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Predicted Domain #1

Region A:
Residues: [1-116]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRVLHPIFL FGKTSFLYSG CSKFGGRLFN NSIVHGWLRT RSYALASGLH PLRKQKLAHF  60
   61 EDLANANMSD PYMQAKLYKE LADNFPEAII SRYETQGVAR NSACDRYYQE ALRKKS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	6.045757
Match:	2aneA
Description:	Crystal structure of N-terminal domain of E.Coli Lon Protease
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [117-248]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WSRSLSNNIS LSQSSSSPAT SSFSDPKAFS AGVPKFTSDT SSTVSSTPSL NHSLQNSMPP  60
   61 STPTPPPVWA PTIVSSALGT SSKTPVYVVV DEPRFTKFFR IFKFIAGLSV ASYFVLLGMS 120
  121 IFAETSGLNN IM

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [249-517]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TNTTEQEPME ERAINVRFSD VQGVDEAKEE LEEIVDFLRD PTHFTRLGGK LPRGVLLTGP  60
   61 PGTGKTMLAR AVAGEANVPF FFMSGSQFDE MYVGVGAKRV RELFAAARKQ APSIIFIDEL 120
  121 DAIGQKRNAR DAAHMRQTLN QLLVDLDGFS KNEDLAHPVV FIGATNFPES LDPALTRPGR 180
  181 FDRHIHVPLP DVRGRLAILL QHTRHVPLGK DVDLSIIARG TSGFAGADLA NLINQAAVYA 240
  241 SKNLSTAVSM RDLEWSKDRI LMGAERKSA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	67.154902
Match:	1lv7A
Description:	AAA domain of cell division protein FtsH
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hydrolase activity	2.32318595170495	bayes_pls_golite062009
binding	2.0681607836408	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	1.64692747234601	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	1.64482911944641	bayes_pls_golite062009
catalytic activity	1.00104173493322	bayes_pls_golite062009
purine nucleotide binding	0.569910969126728	bayes_pls_golite062009
purine ribonucleotide binding	0.568840867400671	bayes_pls_golite062009
ribonucleotide binding	0.568779924702229	bayes_pls_golite062009
nucleotide binding	0.564275755355315	bayes_pls_golite062009
motor activity	0.50661339105747	bayes_pls_golite062009
protein binding	0.378225828131122	bayes_pls_golite062009
pyrophosphatase activity	0.337450879590656	bayes_pls_golite062009
nucleic acid binding	0.318452816722389	bayes_pls_golite062009
nucleoside-triphosphatase activity	0.31055462644917	bayes_pls_golite062009
ATP binding	0.1860481660648	bayes_pls_golite062009
adenyl ribonucleotide binding	0.152859582615242	bayes_pls_golite062009
adenyl nucleotide binding	0.138615225841109	bayes_pls_golite062009

Predicted Domain #4

Region A:
Residues: [518-570]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FITPENKLMT AYHEGGHALV ALFTKNAMRP YKATIMPRGS SLGMTISLPD MDK

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	4.49
Match:	2di4A
Description:	No description for 2di4A was found.

Predicted Domain #5

Region A:
Residues: [571-709]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSWTREEYLA MLDVTMGGRA AEELLYGKDK ITSGAHNDID KATQVARRMV TEFGMSDRIG  60
   61 PVSLEAEMDN LSPATRALVE SEIKSLLEAS YERSLSLLKS HKKELDALAT ALVDYEFLTA 120
  121 EEMNRVVKGD RDLLRNKLS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	108.0
Match:	2ce7A
Description:	EDTA treated
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: