YRC Public Data Repository - Protein Structure Prediction

Protein:	fap1
Organism:	Schizosaccharomyces pombe
Length:	412 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for fap1.

Description	E-value	Query Range	Subject Range
gi\|88925520, gi\|... - gi\|88944849\|ref\|ZP_01148072.1\| proline dehydrogenase, beta subunit [Desulfotomaculum reducens MI-1],...	213.0	[0..1]	[402..1]
gi\|148228313, gi... - gi\|86577798\|gb\|AAI12956.1\| LOC446949 protein [Xenopus laevis], gi\|148228313\|ref\|NP_001087085.1\| hypo...	210.0	[0..4]	[394..56]
gi\|114599496 - gi\|114599496\|ref\|XP_526883.2\| PREDICTED: dimethylglycine dehydrogenase isoform 2 [Pan troglodytes]	210.0	[0..4]	[394..49]
HGNC:24475\|MIM:6... - dehydrogenase gi\|162318786, gi... - gi\|225000204\|gb\|AAI72462.1\| Dimethylglycine dehydrogenase [synthetic construct], gi\|162318786\|gb\|AAI... gi\|24797151 - gi\|24797151\|ref\|NP_037523.2\| dimethylglycine dehydrogenase precursor [Homo sapiens]	210.0	[0..4]	[394..49]
M2GD_RAT - Dimethylglycine dehydrogenase, mitochondrial OS=Rattus norvegicus GN=Dmgdh PE=1 SV=1	209.0	[0..4]	[394..42]
M2GD_MOUSE - Dimethylglycine dehydrogenase, mitochondrial OS=Mus musculus GN=Dmgdh PE=1 SV=1	208.0	[0..4]	[394..42]

Back

Predicted Domain #1

Region A:
Residues: [1-412]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVKNTSVIIV GAGVFGLSAA LELTKRGGYT IKILDRAPPP VIDGSSVDAN RIIRSDYADA  60
   61 VYCSMGIDAL EEWRTNPLFK EQFYGSGLMF VGRDNVEYRD MSLENLTKMG VSAAKFQTTE 120
  121 ELRKLFPKWI GELNDGEAGY ANFSSGWANA EQSVKSVVNY LAHAGVSFIS GPEGTVEELI 180
  181 TEENVVKGVR TTTGAYMAEK LIFATGAWTA SLLPNDHTRF LATGQPVAYI KLTPEEYIRF 240
  241 LTNPVYLDFD TGFYIFPPTP DGYLKFARHG YGFTRMQNLK SGKVESVPPK KPLVSPILPK 300
  301 EAELDLRRNL QRTYGEEISQ RPFYKTRICY YTDTADAEFV FDYHPDYENL FVCTGGSGHG 360
  361 FKFFPILGKY SIGCMFRELE EPLLKKWRWK KENLEFAALD HSRAGPSRQE LS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	49.69897
Match:	1el5A
Description:	Sarcosine oxidase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor	1.61125987248836	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors	1.07245967881566	bayes_pls_golite062009
catalytic activity	1.03127962968326	bayes_pls_golite062009
dihydrolipoyl dehydrogenase activity	0.681230241795345	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors	0.397770205910041	bayes_pls_golite062009
oxidoreductase activity	0.18223312042771	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: