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View Structure Prediction Details

Protein: ysh1
Organism: Schizosaccharomyces pombe
Length: 775 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ysh1.

Description E-value Query
Range
Subject
Range
CPSF3_MOUSE - Cleavage and polyadenylation specificity factor subunit 3 OS=Mus musculus GN=Cpsf3 PE=1 SV=2
535.0 [0..34] [712..9]
gi|71795627, gi|... - gi|71795627|ref|NP_001025201.1| cleavage and polyadenylation specificity factor 3 [Rattus norvegicus...
534.0 [0..34] [711..9]
gi|194220982 - gi|194220982|ref|XP_001502516.2| PREDICTED: similar to Cleavage and Polyadenylation Specifity Factor...
gi|73979708 - gi|73979708|ref|XP_540075.2| PREDICTED: similar to Cleavage and polyadenylation specificity factor, ...
533.0 [0..34] [712..9]
CPSF3_BOVIN - Cleavage and polyadenylation specificity factor subunit 3 OS=Bos taurus GN=CPSF3 PE=1 SV=1
533.0 [0..34] [712..9]
gi|114576010, gi... - gi|114576010|ref|XP_001154730.1| PREDICTED: hypothetical protein isoform 8 [Pan troglodytes], gi|114...
531.0 [0..34] [712..9]
gi|67969340 - gi|67969340|dbj|BAE01022.1| unnamed protein product [Macaca fascicularis]
531.0 [0..34] [712..9]

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Predicted Domain #1
Region A:
Residues: [1-443]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKRKEFDED APVDPSVSLE FTIFYKGLLS NQCQDLLEFI NLGAGNEVGR SCHVIQYKGK  60
   61 TVMLDAGVHP AYTGLSALPF FDEFDLSTVD VLLISHFHLD HVASLPYVMQ KTNFRGRVFM 120
  121 THPTKAVCKW LLSDYVKVSN VGMEDQLYDE KDLLAAFDRI EAVDYHSTIE VEGIKFTPYH 180
  181 AGHVLGACMY FVEMAGVNIL FTGDYSREED RHLHVAEVPP KRPDVLITES TYGTASHQPR 240
  241 LEKEARLLNI IHSTIRNGGR VLMPVFALGR AQELLLILDE YWNNHLDLRS VPIYYASSLA 300
  301 RKCMAIFQTY VNMMNDNIRK IFAERNPFIF RFVKSLRNLE KFDDIGPSVI LASPGMLQNG 360
  361 VSRTLLERWA PDPRNTLLLT GYSVEGTMAK QITNEPIEIV SLSGQKIPRR MAVEELSFAA 420
  421 HVDYLQNSEF IDLVNADHII LVH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 32.39794
Match: 1e5dA
Description: Rubredoxin oxygen:oxidoreductase (ROO), C-terminal domain; Rubredoxin oxygen:oxidoreductase (ROO), N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 2.32880196921974 bayes_pls_golite062009
binding 1.97803450114143 bayes_pls_golite062009
nucleic acid binding 1.66507162669272 bayes_pls_golite062009
RNA binding 1.48455378212673 bayes_pls_golite062009
catalytic activity 0.941400907161877 bayes_pls_golite062009
protein binding 0.380466845099285 bayes_pls_golite062009
transcription factor binding 0.0852528568191628 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [444-613]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GEQTNMGRLK SALASKFHNR KVDVKVYTPR NCVPLYLPFK GERLVRALGK VAVHKPKEGD  60
   61 IMSGILIQKD ANYKLMSAED LRDFSDLTTT VLTQKQVIPF FSSMELANFH LKQMFGYVKQ 120
  121 SKTKAGQPQY TVMDAITLTL IQEHKLALEW VGNIMNDTIA DSVITILLGI 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [614-775]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESSPASVKLT SHKCNHLHSH LDKPPKVSKE EDRIKKLMMF LDNQFGESMT KTEKGVEIKF  60
   61 EKYEASIDFS TMKVECSNEA LRSRVVHVLS RAINTILPFS EASQNDVSED DFENEESDDD 120
  121 KIFEQQTKIE DDVKNENKTE PVEEQKSEEK NEQPNLKKEE LS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle