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View Structure Prediction Details

Protein: fma2
Organism: Schizosaccharomyces pombe
Length: 426 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for fma2.

Description E-value Query
Range
Subject
Range
MAP2_MOUSE - Methionine aminopeptidase 2 OS=Mus musculus GN=Metap2 PE=1 SV=1
396.0 [0..3] [426..60]
gi|114646288 - gi|114646288|ref|XP_509279.2| PREDICTED: similar to Chain , Human Methionine Aminopeptidase 2 [Pan ...
394.0 [0..60] [426..135]
gi|109098252 - gi|109098252|ref|XP_001106804.1| PREDICTED: methionyl aminopeptidase 2 isoform 1 [Macaca mulatta]
393.0 [0..4] [426..2]
gi|73977617 - gi|73977617|ref|XP_866124.1| PREDICTED: similar to Methionine aminopeptidase 2 (MetAP 2) (Peptidase ...
392.0 [0..60] [426..83]
gi|6980558 - gi|6980558|pdb|1B59|A Chain A, Complex Of Human Methionine Aminopeptidase-2 Complexed With Ovalicin
392.0 [0..62] [426..1]
gi|47477887 - gi|47477887|gb|AAH70892.1| Methionyl aminopeptidase 2 [Rattus norvegicus]
391.0 [0..60] [426..71]

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Predicted Domain #1
Region A:
Residues: [1-426]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSATTTEAT AKDLQEKLSL KENDVVEDDG KVEENDAAEE GASNGEKKKK KKKKSSKKKK  60
   61 TPQEQTNPPT VGLSKIFVNK KYPVGEVCDY AEDNLWRTTD EEKRALDRQN FDQYNDLRRA 120
  121 AEVHRQARQY AQSVIKPGMS MMDVVNTIEN TTRALVEEDG LKSGIGFPTG VSLNHCAAHY 180
  181 TPNAGDTTIL KEKDVMKVDI GVHVNGRIVD SAFTMSFDPQ YDNLLAAVKA ATNKGIEEAG 240
  241 IDARLNEIGE AIQEVMESYE VEINGKTHQV KSIRNLCGHN LDPYIIHGGK SVPIVKGGEE 300
  301 IKMEEGEIFA IETFGSTGRG VVHEDMECSH YAKIPDAGHI PLRLPRAKAL LNTITQNFGT 360
  361 LPFCRRYLDR IGESKYLLAL NNLVSAGIVQ DYPPLCDIRG SYTAQFEHTI ILHPTQKEVV 420
  421 SRGDDY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 109.0
Match: 1b59A
Description: Methionine aminopeptidase, insert domain; Methionine aminopeptidase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 2.7189621129065 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 2.38980167546425 bayes_pls_golite062009
hydrolase activity 1.43646476372001 bayes_pls_golite062009
aminopeptidase activity 0.89399203910285 bayes_pls_golite062009
metallopeptidase activity 0.889549933008962 bayes_pls_golite062009
exopeptidase activity 0.816201549553251 bayes_pls_golite062009
binding 0.668489274805168 bayes_pls_golite062009
protein binding 0.378185804009078 bayes_pls_golite062009
nucleic acid binding 0.202664114377071 bayes_pls_golite062009
catalytic activity 0.148551873544128 bayes_pls_golite062009

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