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View Structure Prediction Details

Protein: mbx2
Organism: Schizosaccharomyces pombe
Length: 372 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mbx2.

Description E-value Query
Range
Subject
Range
gi|34452083 - gi|34452083|gb|AAQ72498.1| MADS-box protein 12 [Petunia x hybrida]
236.0 [0..1] [234..1]
gi|62122355 - gi|62122355|dbj|BAD93172.1| MADS-box transcription factor GbMADS8 [Ginkgo biloba]
233.0 [0..1] [233..1]
gi|31747208 - gi|31747208|gb|AAP57412.1| MADS-box protein 1 [Lycopersicon esculentum]
228.0 [0..1] [234..1]
gi|34979582 - gi|34979582|gb|AAQ83835.1| MADS box protein [Asparagus officinalis]
227.0 [0..1] [232..1]
gi|89258366 - gi|89258366|gb|ABD65406.1| MADS-box protein [Diospyros kaki]
227.0 [0..1] [234..1]
gi|63014399 - gi|63014399|gb|AAY25580.1| AGL6 [Amborella trichopoda]
226.0 [0..1] [232..1]
gi|1206005, gi|7... - pir||T09571 MADS box protein MADS2 - Monterey pine, gi|1206005|gb|AAD09207.1| putative MADS-box fami...
226.0 [0..1] [233..1]
gi|1702951, gi|7... - pir||T10486 MADS box protein - Canadian red pine, gi|1702951|emb|CAA70822.1| MADS-box family transcr...
226.0 [0..1] [233..1]
gi|63094573 - gi|63094573|gb|AAY30858.1| MADS-box transcription factor [Prunus dulcis]
225.0 [0..1] [234..1]

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Predicted Domain #1
Region A:
Residues: [1-85]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGRKKISIAP ITDDRSRSVT FVKRKQGLYK KAYELAVLAD CEVAVTVIDR KGRLHVFCSS  60
   61 DYQRTLQQLN TLSIYELKNR SHFSS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 29.221849
Match: 1tqeP
Description: Mechanism of recruitment of class II histone deacetylases by myocyte enhancer factor-2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleic acid binding 3.20423226810641 bayes_pls_golite062009
DNA binding 3.19357863925229 bayes_pls_golite062009
binding 3.13725722282473 bayes_pls_golite062009
transcription regulator activity 3.13318816174147 bayes_pls_golite062009
transcription factor activity 2.59884999361198 bayes_pls_golite062009
sequence-specific DNA binding 2.01575603719104 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.0615361674883 bayes_pls_golite062009
protein binding 1.0452482001033 bayes_pls_golite062009
transcription activator activity 0.69462470268703 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [86-199]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPVEESSTVS PETTTGSFTP LNNKHLKSQD QPLSDSQLDT GDSPATSETT VQDYNPQVQS  60
   61 YCRPEPLSSN HVRSCPPFPP TQHHHPHTRP PHHPPHPHFH NNNYPPPYCF QSPV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [200-372]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPGATVPLQH HSPYPSDNGF PGHRRQTHFA PYYYPQRATS PSLKQVPTYL GTHVLQQDQS  60
   61 TYDQKVLMPP ASYLSSPNQY TLKNVSPGNP ACPPFLYEHP NPQLTPEMFD VKQGSPIPPT 120
  121 AYSGSSCETS QHTIANTPFL AYDRSPSLTN QEAESSFQDV ASISPHSLSD VKY

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle